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Part Used : ราก

Activity : P-GLYCOPROTEIN INHIBITION

Solvent/Active Compound : coumarin, volatile oil

Type of experiment : in vitro

Type of animal : -

Type of study : -

N(Total) : -

N(Treatment) : -

Sex : -

Age : -

Route : -

Dose/Conc.(herb) : -

Duration : -

Type of interaction : Pharmacokinetics

Interaction with drug : -

Dose/Conc.(drug) : -

Result : Positive

Remark : Cou and VO could significantly reduce the expression level of P-gp. Cou combined with VO also could reduce the expression level of P-gp. These results indicated that Cou and VO could down-regulate the expression of P-gp.

Note : Cou = coumarin, VO = volatile oil, P-gp = P-glycoprotein

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