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Part Used : ดอก

Activity : URIDINE DIPHOSPHATE GLUCURONYLTRANSFERASE INHIBITION

Solvent/Active Compound : dimethyl sulfoxide (DMSO): methanol (1:1, v/v)

Type of experiment : in vitro

Type of animal : -

Type of study : -

N(Total) : -

N(Treatment) : -

Sex : -

Age : -

Route : -

Dose/Conc.(herb) : Elderberry extract >500 microgram/mL

Duration : -

Type of interaction : Pharmacokinetics

Interaction with drug : -

Dose/Conc.(drug) : -

Result : Negative

Remark : Result: Elderberry had no apparent inhibitory effects on any of the five UGTs (UGT1A1, UGT1A4, UGT1A6, UGT1A9, and UGT2B7)

Note : Five berries (bilberry, blueberry, cranberry, elderberry, and raspberry ketones) are unlikely to cause clinically significant herb-drug interactions mediated via inhibition of UGT enzymes involved in drug metabolism.

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