Synonym |
Thai / English name |
Part Used : ไม่ระบุActivity : CYP2C INHIBITIONSolvent/Active Compound : diosminType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 1-100 micromolarDuration : -Type of interaction : PharmacokineticsInteraction with drug : TolbutamideDose/Conc.(drug) : 1 millimolarResult : NegativeRemark : Diosmin failed to inhibit CYP2C activity.
Part Used : น้ำจากผลActivity : CYP2C INHIBITIONSolvent/Active Compound : NaringeninType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 1-100 micromolarDuration : -Type of interaction : PharmacokineticsInteraction with drug : TolbutamideDose/Conc.(drug) : 1 millimolarResult : PositiveRemark : Naringenin from grapefruit juice produced 81.6% and 51.3% CYP2C inhibition at 100 and 10 micromolar, respectively. However, no significant effect was observed in the presence of 1 micromolar of this compound.
Part Used : ไม่ระบุActivity : CYP2C INHIBITIONSolvent/Active Compound : PoncirinType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 1-100 micromolarDuration : -Type of interaction : PharmacokineticsInteraction with drug : TolbutamideDose/Conc.(drug) : 1 millimolarResult : NegativeRemark : Poncirin from Citrus failed to inhibit CYP2C activity.
Part Used : น้ำจากผลActivity : CYP2C INHIBITIONSolvent/Active Compound : NaringinType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 1-100 micromolarDuration : -Type of interaction : PharmacokineticsInteraction with drug : TolbutamideDose/Conc.(drug) : 1 millimolarResult : NegativeRemark : Naringin from grapefruit juice failed to inhibit CYP2C activity.
Part Used : ไม่ระบุActivity : CYP2C INHIBITIONSolvent/Active Compound : HesperetinType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 1-100 micromolarDuration : -Type of interaction : PharmacokineticsInteraction with drug : TolbutamideDose/Conc.(drug) : 1 millimolarResult : PositiveRemark : Hesperetin produced 56.1% CYP2C inhibition at 100 micromolar. However, no significant effect was observed in the presence of 10 and 1 micromolar of this compound.
Part Used : ไม่ระบุActivity : CYP2C INHIBITIONSolvent/Active Compound : HesperedinType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 1-100 micromolarDuration : -Type of interaction : PharmacokineticsInteraction with drug : TolbutamideDose/Conc.(drug) : 1 millimolarResult : NegativeRemark : Hesperedin failed to inhibit CYP2C activity.