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| Thai / English name |
Part Used : ผลActivity : DRUG INTERACTIONSolvent/Active Compound : hidroalcoholic / 10% synephrineType of experiment : in vivoType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : 164 mg/kgDuration : a single doseType of interaction : PharmacokineticsInteraction with drug : AmiodaroneDose/Conc.(drug) : 50 mg/kgResult : PositiveRemark : - It deserves to be highlighted the significant increase of the peak plasma concentration of amiodarone in rats pre-treated with C. aurantium extract, while the extent of systemic exposure was comparable between both groups.Note : - This paper reports, data on the potential of herb-drug interaction between C. aurantium extract and amiodarone.
Part Used : ผลActivity : EFFECTS ON PHARMACOKINETICSolvent/Active Compound : hidroalcoholic / 10% synephrineType of experiment : in vivoType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : 164 mg/kgDuration : a single doseType of interaction : PharmacokineticsInteraction with drug : AmiodaroneDose/Conc.(drug) : 50 mg/kgResult : PositiveRemark : - It deserves to be highlighted the significant increase of the peak plasma concentration of amiodarone in rats pre-treated with C. aurantium extract, while the extent of systemic exposure was comparable between both groups.Note : - This paper reports, data on the potential of herb-drug interaction between C. aurantium extract and amiodarone.
Part Used : ผลActivity : DRUG INTERACTIONSolvent/Active Compound : hidroalcoholic / 10% synephrineType of experiment : in vivoType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : 164 mg/kgDuration : 14 dayType of interaction : PharmacokineticsInteraction with drug : AmiodaroneDose/Conc.(drug) : 50 mg/kg on the 15th dayResult : PositiveRemark : - It deserves to be highlighted the significant increase of the peak plasma concentration of amiodarone in rats pre-treated with C. aurantium extract, while the extent of systemic exposure was comparable between both groups.Note : - This paper reports, data on the potential of herb-drug interaction between C. aurantium extract and amiodarone.
Part Used : ผลActivity : EFFECTS ON PHARMACOKINETICSolvent/Active Compound : hidroalcoholic / 10% synephrineType of experiment : in vivoType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : 164 mg/kgDuration : 14 dayType of interaction : PharmacokineticsInteraction with drug : AmiodaroneDose/Conc.(drug) : 50 mg/kg on the 15th dayResult : PositiveRemark : - It deserves to be highlighted the significant increase of the peak plasma concentration of amiodarone in rats pre-treated with C. aurantium extract, while the extent of systemic exposure was comparable between both groups.Note : - This paper reports, data on the potential of herb-drug interaction between C. aurantium extract and amiodarone.
