Part Used : น้ำมันหอมระเหย
Activity : DRUG INTERACTION
Solvent/Active Compound : Tea tree oil
Type of experiment : in vitro
Type of animal : -
N(Total) : -
N(Treatment) : -
Route : -
Dose/Conc.(herb) : The essential oils at starting stock concentrations of 128 mg/ml in acetone were combined with ciprofloxacin or amphotericin at a starting stock concentration of 0.01 mg/ml in nine different ratios i.e. 9 : 1; 8 : 2; 7 : 3; 6 : 4; 5 : 5; 4 : 6; 3 : 7; 2 : 8 and 1 : 9.
Duration : -
Type of interaction : Pharmacokinetics
Interaction with drug : Amphotericin B
Dose/Conc.(drug) : The essential oils at starting stock concentrations of 128 mg/ml in acetone were combined with ciprofloxacin or amphotericin at a starting stock concentration of 0.01 mg/ml in nine different ratios i.e. 9 : 1; 8 : 2; 7 : 3; 6 : 4; 5 : 5; 4 : 6; 3 : 7; 2 : 8 and 1 : 9.
Remark : Amphotericin B in combination with M. alternifolia oil show a predominantly antagonistic profile against C. albicans only two ratios (6 : 4, fractional inhibitory concentration (FIC) 0.93) and (1 : 9, FIC 0.95) having a slight synergistic effect.