ฐานข้อมูลอันตรกิริยาระหว่างสมุนไพรกับยาแผนปัจจุบัน

Part Used : น้ำมันหอมระเหย

Activity : DRUG INTERACTION

Solvent/Active Compound : Tea tree oil

Type of experiment : in vitro

Type of animal : -

Type of study : -

N(Total) : -

N(Treatment) : -

Sex : -

Age : -

Route : -

Dose/Conc.(herb) : The essential oils at starting stock concentrations of 128 mg/ml in acetone were combined with ciprofloxacin or amphotericin at a starting stock concentration of 0.01 mg/ml in nine different ratios i.e. 9 : 1; 8 : 2; 7 : 3; 6 : 4; 5 : 5; 4 : 6; 3 : 7; 2 : 8 and 1 : 9.

Duration : -

Type of interaction : Pharmacokinetics

Interaction with drug : Ciprofloxacin

Dose/Conc.(drug) : The essential oils at starting stock concentrations of 128 mg/ml in acetone were combined with ciprofloxacin or amphotericin at a starting stock concentration of 0.01 mg/ml in nine different ratios i.e. 9 : 1; 8 : 2; 7 : 3; 6 : 4; 5 : 5; 4 : 6; 3 : 7; 2 : 8 and 1 : 9.

Result : Positive

Remark : When M. alternifolia oil is combined with ciprofloxacin and tested against S. aureus, antagonism was noted for all ratios. However only five antagonistic ratios were noted for S. aureus (ratios 9:1, 8:2, 6:4 and 5:5) and three antagonistic ratios (9:1, 8:2 and 1:9) for K. pneumoniae.

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