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Part Used : รากActivity : CYP3A4 INHIBITIONSolvent/Active Compound : 18beta-glycyrrhetic acid (18beta-GA), 18alpha-glycyrrhetic acid (18alpha-GA)Type of experiment : in silicoType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : -Duration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : Result: Both 18beta-GA and 18alpha-GA could form a strong hydrogen bond with Arg212 (1.7 angstroms and 1.6 angstroms).