LEGUMINOSAE (FABACEAE) - PAPILIONOIDEAE Glycyrrhiza spp.  

 Synonym

    none ...
 Thai / English name

  • Glycyrrhiza spp.

[1-1] of 1 article(s) found

 หน้า  1  

[1] INHIBITORY EFFECTS OF HERBAL CONSTITUENTS ON P-GLYCOPROTEIN IN VITRO AND IN VIVO: HERB-DRUG INTERACTIONS MEDIATED VIA P-GP.
LI,XUE;HU,JINPING;WANG,BAOLIAN;ET AL.
TOXICOL APPL PHARMACOL 2014 Vol.275(2),163-75  $53165 [Full]

Part Used : ราก
Activity : CYP3A4 INHIBITION
Solvent/Active Compound : 18beta-glycyrrhetic acid (18beta-GA), 18alpha-glycyrrhetic acid (18alpha-GA)
Type of experiment : in silico
Type of animal : -
Type of study : -
N(Total) : -
N(Treatment) : -
Sex : -
Age : -
Route : -
Dose/Conc.(herb) : -
Duration : -
Type of interaction : Pharmacokinetics
Interaction with drug : -
Dose/Conc.(drug) : -
Result : Positive
Remark : Result: Both 18beta-GA and 18alpha-GA could form a strong hydrogen bond with Arg212 (1.7 angstroms and 1.6 angstroms).


 หน้า  1