| Synonym |
| Thai / English name |
Part Used : เหง้าActivity : DRUG INTERACTIONSolvent/Active Compound : curcuminType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 25 micrograms/mlDuration : -Type of interaction : PharmacodynamicsInteraction with drug : Daunorubicin*/Daunomycin/RubidomycinDose/Conc.(drug) : -Result : PositiveRemark : Curcumin, demethoxycurcumin and bisdemethoxycurcumin significantly increased the transport of daunorubisin in the a-b direction. However, the b-a transport of daunorubicin was significantly decreased by curcumin and demethoxycurcumin but was not effects by bisdemethoxycurcumin. The net efflux ratio was reduced to 1.5, 1.0 and 2.0 in the present of curcumin, demethoxycurcumin and bisdemethoxycurcumn, respectively
Part Used : เหง้าActivity : DRUG INTERACTIONSolvent/Active Compound : demethoxycurcuminType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 35 micrograms/mlDuration : -Type of interaction : PharmacodynamicsInteraction with drug : Daunorubicin*/Daunomycin/RubidomycinDose/Conc.(drug) : -Result : PositiveRemark : Curcumin, demethoxycurcumin and bisdemethoxycurcumin significantly increased the transport of daunorubisin in the a-b direction. However, the b-a transport of daunorubicin was significantly decreased by curcumin and demethoxycurcumin but was not effects by bisdemethoxycurcumin. The net efflux ratio was reduced to 1.5, 1.0 and 2.0 in the present of curcumin, demethoxycurcumin and bisdemethoxycurcumn, respectively
Part Used : เหง้าActivity : DRUG INTERACTIONSolvent/Active Compound : bisdemethoxycurcuminType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 50 micrograms/mlDuration : -Type of interaction : PharmacodynamicsInteraction with drug : Daunorubicin*/Daunomycin/RubidomycinDose/Conc.(drug) : -Result : PositiveRemark : Curcumin, demethoxycurcumin and bisdemethoxycurcumin significantly increased the transport of daunorubisin in the a-b direction. However, the b-a transport of daunorubicin was significantly decrease by curcumin and demethoxycurcumin but was not effects by bisdemethoxycurcumin. The net efflux ratio was reduced to 1.5, 1.0 and 2.0 in the present of curcumin, demethoxycurcumin and bisdemethoxycurcumn, respectively
