Part Used : เหง้า
Activity : CYTOCHROME P-450 INHIBITION
Solvent/Active Compound : anthraquinone
Type of experiment : in vivo
Type of animal : rat
N(Total) : -
N(Treatment) : -
Route : Oral administration
Dose/Conc.(herb) : Rhuem emodi 0.4 g/kg
Duration : One time
Type of interaction : Pharmacokinetics
Interaction with drug : Pentobarbital*/Pentobarbitone
Dose/Conc.(drug) : -
Remark : Oral dose of total anthraquinone fraction of Rhuem emodi 0.4 g/kg significantly increases the pentobarbitone sleep time when compared to the control, indicating the cytochrome P450 inhibition activity.