Synonym |
Thai / English name |
Part Used : รากActivity : CYP3A INDUCTIONSolvent/Active Compound : EmodinType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 10 micromolarsDuration : -Type of interaction : PharmacokineticsInteraction with drug : Midazolam*/Versed/DormicumDose/Conc.(drug) : -Result : PositiveRemark : Type of experiment: Human liver microsomes Result: Emodin increased the metabolic rate of midazolam by approximately 35% compared to the control.
Part Used : รากActivity : CYP3A4/5 INDUCTIONSolvent/Active Compound : EmodinType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 10 micromolarsDuration : -Type of interaction : PharmacokineticsInteraction with drug : Midazolam*/Versed/DormicumDose/Conc.(drug) : -Result : PositiveRemark : Type of experiment: Human liver microsomes Result: Emodin increased the metabolic rate of midazolam by approximately 35% compared to the control.
Part Used : รากActivity : CYP3A INDUCTIONSolvent/Active Compound : chrysophanolType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 10 micromolarsDuration : -Type of interaction : PharmacokineticsInteraction with drug : Midazolam*/Versed/DormicumDose/Conc.(drug) : -Result : EquivocalRemark : Type of experiment: Human liver microsomes Result: Expectedly, chrysophanol did not show a significant activation on CYP3A activity.