Synonym |
Thai / English name |
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : ganoderma triterpenes (GTS)Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : -Duration : -Type of interaction : PharmacodynamicsInteraction with drug : Docetaxel*/TaxotereDose/Conc.(drug) : -Result : PositiveRemark : Type of experiment: human cervical carcinoma HeLa cells and human non-small lung carcinoma A549 cells Results: The combinations targeting GTS with docetaxel resulted in a synergistic interaction in HeLa cells and an additive interaction in A549 cells.
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : ganoderma triterpenes (GTS)Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : -Duration : -Type of interaction : PharmacodynamicsInteraction with drug : Cisplatin*/CDDPDose/Conc.(drug) : -Result : PositiveRemark : Type of experiment: human cervical carcinoma HeLa cells and human non-small lung carcinoma A549 cells Results: The interaction between cisplatin and GTS showed different results, i.e. synergism, additive or antagonism, if we change the relative potency of their cytotoxicity. The interaction might be antagonism when the cytotoxicity of one kind of medicine was stronger than that of the other and it might be synergism when the cytotoxicity of the two medicines was similar.
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : humanType of animal : -Type of study : Cross-sectionN(Total) : 56 (M/F = 24/32)N(Treatment) : 1Sex : Both sexAge : 68.7 +/- 7.7 yrsRoute : Oral administrationDose/Conc.(herb) : -Duration : -Type of interaction : PharmacodynamicsInteraction with drug : Aspirin*/Acetylsalicylic acid/ASA/EcosprinDose/Conc.(drug) : -Result : PositiveRemark : เห็ดหลินจือมีฤทธิ์ยับยั้งการเกาะกลุ่มของเกล็ดเลือด จึงเสริมฤทธิ์ของ aspirin เพิ่มความเสี่ยงของการเกิดภาวะเลือดออกNote : Data incomplete, data from review article
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : -Duration : -Type of interaction : PharmacokineticsInteraction with drug : DigoxinDose/Conc.(drug) : -Result : PositiveRemark : Use of Ganoderma lucidum in the treatment of cancer and indicate potential pharmacokinetic interaction or potentiation of Ganoderma lucidum with other drug treatmentsNote : Data incomplete