GANODERMATACEAE Ganoderma lucidum  (Fr.) Karst.

 Synonym

  • GANODERMATACEAE Polyporus lucidum  Fr.
 Thai / English name

  • เห็ดหลินจือ*

[1-3] of 3 article(s) found

 หน้า  1  

[1] INTERACTION OF GANODERMA TRITERPENES WITH DOCETAXEL AND CISPLATIN IN CYTOTOXICITY AGAINST HUMAN CARCINOMA CELLS.
YUE Q-X,GUAN S-H,XIE F-B,ET AL.
ZHONGGUO TIANRAN YAOWU 2008 Vol.6(5),367-71  $24549 [Full]

Part Used : ไม่ระบุ
Activity : DRUG INTERACTION
Solvent/Active Compound : ganoderma triterpenes (GTS)
Type of experiment : in vitro
Type of animal : -
Type of study : -
N(Total) : -
N(Treatment) : -
Sex : -
Age : -
Route : -
Dose/Conc.(herb) : -
Duration : -
Type of interaction : Pharmacodynamics
Interaction with drug : Docetaxel*/Taxotere
Dose/Conc.(drug) : -
Result : Positive
Remark : Type of experiment: human cervical carcinoma HeLa cells and human non-small lung carcinoma A549 cells Results: The combinations targeting GTS with docetaxel resulted in a synergistic interaction in HeLa cells and an additive interaction in A549 cells.

Part Used : ไม่ระบุ
Activity : DRUG INTERACTION
Solvent/Active Compound : ganoderma triterpenes (GTS)
Type of experiment : in vitro
Type of animal : -
Type of study : -
N(Total) : -
N(Treatment) : -
Sex : -
Age : -
Route : -
Dose/Conc.(herb) : -
Duration : -
Type of interaction : Pharmacodynamics
Interaction with drug : Cisplatin*/CDDP
Dose/Conc.(drug) : -
Result : Positive
Remark : Type of experiment: human cervical carcinoma HeLa cells and human non-small lung carcinoma A549 cells Results: The interaction between cisplatin and GTS showed different results, i.e. synergism, additive or antagonism, if we change the relative potency of their cytotoxicity. The interaction might be antagonism when the cytotoxicity of one kind of medicine was stronger than that of the other and it might be synergism when the cytotoxicity of the two medicines was similar.

[2] การใช้สมุนไพรและผลิตภัณฑ์เสริมอาหารที่มีโอกาสเกิดอันตรกิริยากับยาที่ใช้ในผู้ป่วยโรคเรื้อรัง
ชุลีกร สอนสุวิทย์, ชบาไพร โพธิ์สุยะ, ดวงกมล จรูญวนิชกุล และคณะ
วารสารไทยเภสัชศาสตร์และวิทยาการสุขภาพ 2012 Vol.7(4),149-54  $46679 [Full]

Part Used : ไม่ระบุ
Activity : DRUG INTERACTION
Solvent/Active Compound : -
Type of experiment : human
Type of animal : -
Type of study : Cross-section
N(Total) : 56 (M/F = 24/32)
N(Treatment) : 1
Sex : Both sex
Age : 68.7 +/- 7.7 yrs
Route : Oral administration
Dose/Conc.(herb) : -
Duration : -
Type of interaction : Pharmacodynamics
Interaction with drug : Aspirin*/Acetylsalicylic acid/ASA/Ecosprin
Dose/Conc.(drug) : -
Result : Positive
Remark : เห็ดหลินจือมีฤทธิ์ยับยั้งการเกาะกลุ่มของเกล็ดเลือด จึงเสริมฤทธิ์ของ aspirin เพิ่มความเสี่ยงของการเกิดภาวะเลือดออก
Note : Data incomplete, data from review article

[3] HIGH-RESOLUTIION BIOGUIDED SCREENING OF GANODERMA CAPENSE FOR P-GP MODULATING ACTIVITY.
TA HP,MACIUK A,VAUTIER S,ET AL.
PLANTA MED 2008 Vol.74(09),PC85  404334 [Abstract]

Part Used : ไม่ระบุ
Activity : DRUG INTERACTION
Solvent/Active Compound : -
Type of experiment : in vitro
Type of animal : -
Type of study : -
N(Total) : -
N(Treatment) : -
Sex : -
Age : -
Route : -
Dose/Conc.(herb) : -
Duration : -
Type of interaction : Pharmacokinetics
Interaction with drug : Digoxin
Dose/Conc.(drug) : -
Result : Positive
Remark : Use of Ganoderma lucidum in the treatment of cancer and indicate potential pharmacokinetic interaction or potentiation of Ganoderma lucidum with other drug treatments
Note : Data incomplete


 หน้า  1