ฐานข้อมูลอันตรกิริยาระหว่างสมุนไพรกับยาแผนปัจจุบัน

Part Used : น้ำมัน

Activity : CYP3A4 INDUCTION

Solvent/Active Compound : Efalex*

Type of experiment : in vitro

Type of animal : -

Type of study : -

N(Total) : -

N(Treatment) : -

Sex : -

Age : -

Route : -

Dose/Conc.(herb) : 100 microgram/ml

Duration : -

Type of interaction : Pharmacokinetics

Interaction with drug : -

Dose/Conc.(drug) : -

Result : Negative

Remark : *Efalex comprised of fish oil mixture with evening primrose oil - Efalex caused 6.1+/-1.7 fold-induction of CYP1A2 mRNA expression. However it could not significantly induced mRNA expression of CYP3A4 and MDR1.

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