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ONAGRACEAE Oenothera biennis L.

Synonym

ONAGRACEAE Oenothera communis H. Lev.
ONAGRACEAE Oenothera graveolens Gilib
ONAGRACEAE Oenothera lamarkiana Ser.
ONAGRACEAE Onagra biennis Scop

Thai / English name

EVENING PRIMROSE*

[1-2] of 2 article(s) found

หน้า 1

[1] INTERACTIONS BETWEEN HERBAL AND CONVENTIONAL MEDICINES: THE ROLE OF CYTOCHROME P450 ENZYMES AND P-GLYCOPROTEIN.
WILLIAMSON EM
PHARMACOLOGYONLINE 2006 Vol.2(),200-5 $29296 [Full]

Part Used : ไม่ระบุ
Activity : CYP3A4 INHIBITION

Solvent/Active Compound : oil

Type of experiment : in vitro
Type of animal : -

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : -
Dose/Conc.(herb) : -

Duration : -
Type of interaction : Pharmacokinetics

Interaction with drug : Phenothiazines*/Phenothiazine/PTZ/10H-Phenothiazine/Thiodiphenylamine
Dose/Conc.(drug) : -

Result : Positive

Remark : Oil moderately inhibits in vitro activity of CYP3A4, CYP1A2, CYP2C9, CYP2D6 and CYP2C19. Possible clinical interaction with phenothiazines.

Note : Data incomplete, data from review article.

Part Used : ไม่ระบุ
Activity : CYP1A2 INHIBITION

Solvent/Active Compound : oil

Type of experiment : in vitro
Type of animal : -

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : -
Dose/Conc.(herb) : -

Duration : -
Type of interaction : Pharmacokinetics

Interaction with drug : Phenothiazines*/Phenothiazine/PTZ/10H-Phenothiazine/Thiodiphenylamine
Dose/Conc.(drug) : -

Result : Positive

Remark : Oil moderately inhibits in vitro activity of CYP3A4, CYP1A2, CYP2C9, CYP2D6 and CYP2C19. Possible clinical interaction with phenothiazines.

Note : Data incomplete, data from review article.

Part Used : ไม่ระบุ
Activity : CYP2C19 INHIBITION

Solvent/Active Compound : oil

Type of experiment : in vitro
Type of animal : -

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : -
Dose/Conc.(herb) : -

Duration : -
Type of interaction : Pharmacokinetics

Interaction with drug : Phenothiazines*/Phenothiazine/PTZ/10H-Phenothiazine/Thiodiphenylamine
Dose/Conc.(drug) : -

Result : Positive

Remark : Oil moderately inhibits in vitro activity of CYP3A4, CYP1A2, CYP2C9, CYP2D6 and CYP2C19. Possible clinical interaction with phenothiazines.

Note : Data incomplete, data from review article.

Part Used : ไม่ระบุ
Activity : CYP2C9 INHIBITION

Solvent/Active Compound : oil

Type of experiment : in vitro
Type of animal : -

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : -
Dose/Conc.(herb) : -

Duration : -
Type of interaction : Pharmacokinetics

Interaction with drug : Phenothiazines*/Phenothiazine/PTZ/10H-Phenothiazine/Thiodiphenylamine
Dose/Conc.(drug) : -

Result : Positive

Remark : Oil moderately inhibits in vitro activity of CYP3A4, CYP1A2, CYP2C9, CYP2D6 and CYP2C19. Possible clinical interaction with phenothiazines.

Note : Data incomplete, data from review article.

Part Used : ไม่ระบุ
Activity : DRUG INTERACTION

Solvent/Active Compound : oil

Type of experiment : in vitro
Type of animal : -

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : -
Dose/Conc.(herb) : -

Duration : -
Type of interaction : Pharmacokinetics

Interaction with drug : Phenothiazines*/Phenothiazine/PTZ/10H-Phenothiazine/Thiodiphenylamine
Dose/Conc.(drug) : -

Result : Positive

Remark : Oil moderately inhibits in vitro activity of CYP3A4, CYP1A2, CYP2C9, CYP2D6 and CYP2C19. Possible clinical interaction with phenothiazines.

Note : Data incomplete, data from review article.

Part Used : ไม่ระบุ
Activity : CYP2D6 INHIBITION

Solvent/Active Compound : oil

Type of experiment : in vitro
Type of animal : -

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : -
Dose/Conc.(herb) : -

Duration : -
Type of interaction : Pharmacokinetics

Interaction with drug : Phenothiazines*/Phenothiazine/PTZ/10H-Phenothiazine/Thiodiphenylamine
Dose/Conc.(drug) : -

Result : Positive

Remark : Oil moderately inhibits in vitro activity of CYP3A4, CYP1A2, CYP2C9, CYP2D6 and CYP2C19. Possible clinical interaction with phenothiazines.

Note : Data incomplete, data from review article.

[2] INTERACTIONS BETWEEN HERBAL AND CONVENTIONAL MEDICINES: THE ROLE OF CYTOCHROME P450 ENZYMES AND P-GLYCOPROTEIN.
WILLIAMSON EM
PHARMACOLOGYONLINE 2006 Vol.(2),200-5 $56391 [Full]

Part Used : ไม่ระบุ
Activity : CYP3A4 INHIBITION

Solvent/Active Compound : oil

Type of experiment : in vitro
Type of animal : -

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : -
Dose/Conc.(herb) : -

Duration : -
Type of interaction : Pharmacokinetics

Interaction with drug : Phenothiazines*/Phenothiazine/PTZ/10H-Phenothiazine/Thiodiphenylamine
Dose/Conc.(drug) : -

Result : Positive

Remark : Oil moderately inhibits in vitro activity of CYP3A4, CYP1A2, CYP2C9, CYP2D6 and CYP2C19. Possible clinical interaction with phenothiazines.

Note : Data from review, data incomplete.

Part Used : ไม่ระบุ
Activity : CYP2C19 INHIBITION

Solvent/Active Compound : oil

Type of experiment : in vitro
Type of animal : -

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : -
Dose/Conc.(herb) : -

Duration : -
Type of interaction : Pharmacokinetics

Interaction with drug : Phenothiazines*/Phenothiazine/PTZ/10H-Phenothiazine/Thiodiphenylamine
Dose/Conc.(drug) : -

Result : Positive

Remark : Oil moderately inhibits in vitro activity of CYP3A4, CYP1A2, CYP2C9, CYP2D6 and CYP2C19. Possible clinical interaction with phenothiazines.

Note : Data from review, data incomplete.

Part Used : ไม่ระบุ
Activity : CYP2C9 INHIBITION

Solvent/Active Compound : oil

Type of experiment : in vitro
Type of animal : -

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : -
Dose/Conc.(herb) : -

Duration : -
Type of interaction : Pharmacokinetics

Interaction with drug : Phenothiazines*/Phenothiazine/PTZ/10H-Phenothiazine/Thiodiphenylamine
Dose/Conc.(drug) : -

Result : Positive

Remark : Oil moderately inhibits in vitro activity of CYP3A4, CYP1A2, CYP2C9, CYP2D6 and CYP2C19. Possible clinical interaction with phenothiazines.

Note : Data from review, data incomplete.

Part Used : ไม่ระบุ
Activity : CYP2D6 INHIBITION

Solvent/Active Compound : oil

Type of experiment : in vitro
Type of animal : -

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : -
Dose/Conc.(herb) : -

Duration : -
Type of interaction : Pharmacokinetics

Interaction with drug : Phenothiazines*/Phenothiazine/PTZ/10H-Phenothiazine/Thiodiphenylamine
Dose/Conc.(drug) : -

Result : Positive

Remark : Oil moderately inhibits in vitro activity of CYP3A4, CYP1A2, CYP2C9, CYP2D6 and CYP2C19. Possible clinical interaction with phenothiazines.

Note : Data from review, data incomplete.

หน้า 1

EN

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