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Part Used : ไม่ระบุActivity : ARYL HYDROCARBON RECEPTOR BINDING INHIBITIONSolvent/Active Compound : KaempferolType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : Kaempferol 6.3 mcg/mLDuration : MCF-10A cells were treated with kaempferol for 48 hType of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : Result: Kaempferol and isorhamnetin completely blocked the increase in reporter activity by benzo[a]pyrene, which is an AhR agonist.Note : Solvent/compound: Ginkgo biloba extract contained 6.2% w/w terpene trilactones, consisting of bilobalide (2.8%), ginkgolide A (1.1%), ginkgolide B (0.3%), ginkgolide C (1.4%), and ginkgolide J (0.6%). It also contained 21% w/w flavonols (as sum of the aglycone and glycosides), consisting of quercetin (10.6%), kaempferol (6.3%), and isorhamnetin (4.1%).
Part Used : ไม่ระบุActivity : ARYL HYDROCARBON RECEPTOR BINDING INHIBITIONSolvent/Active Compound : isorhamnetinType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : isorhamnetin 4.1 mcg/mLDuration : MCF-10A cells were treated with isorhamnetin for 48 hType of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : Result: Kaempferol and isorhamnetin completely blocked the increase in reporter activity by benzo[a]pyrene, which is an AhR agonist.Note : Solvent/compound: Ginkgo biloba extract contained 6.2% w/w terpene trilactones, consisting of bilobalide (2.8%), ginkgolide A (1.1%), ginkgolide B (0.3%), ginkgolide C (1.4%), and ginkgolide J (0.6%). It also contained 21% w/w flavonols (as sum of the aglycone and glycosides), consisting of quercetin (10.6%), kaempferol (6.3%), and isorhamnetin (4.1%).