Synonym |
Thai / English name |
Part Used : ไม่ระบุActivity : CYTOCHROME P-450 LEVEL INCREASESolvent/Active Compound : -Type of experiment : in vivoType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : 0.5% ginkgo biloba ext. (GBE)Duration : 2 weeksType of interaction : PharmacodynamicsInteraction with drug : NicardipineDose/Conc.(drug) : -Result : PositiveRemark : GBE significantly increased hepatic P450 content.Note : Data incomplete
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : in vivoType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : 0.5% ginkgo biloba ext. (GBE)Duration : 2 weeksType of interaction : PharmacodynamicsInteraction with drug : NicardipineDose/Conc.(drug) : -Result : PositiveRemark : GBE significantly increased hepatic P450 content.Note : Data incomplete
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : in vivoType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : 0.5% ginkgo biloba ext. (GBE)Duration : 2 weeksType of interaction : PharmacokineticsInteraction with drug : NicardipineDose/Conc.(drug) : -Result : PositiveRemark : GBE administration resulted in a significant decrease in maximal nicardipine plasma conc. (Cmax) and the 23-h area under curve (AUC0-23).Note : Data incomplete
Part Used : ไม่ระบุActivity : EFFECTS ON PHARMACOKINETICSolvent/Active Compound : -Type of experiment : in vivoType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : 0.5% ginkgo biloba ext. (GBE)Duration : 2 weeksType of interaction : PharmacokineticsInteraction with drug : NicardipineDose/Conc.(drug) : -Result : PositiveRemark : GBE administration resulted in a significant decrease in maximal nicardipine plasma conc. (Cmax) and the 23-h area under curve (AUC0-23).Note : Data incomplete
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : Ginkgo biloba extractType of experiment : in vivoType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : -Duration : 4 weeksType of interaction : PharmacokineticsInteraction with drug : NicardipineDose/Conc.(drug) : -Result : PositiveRemark : The hypotensive effect of nicardipine was significantly reduced in the rats fed ginkgo biloba extract for 4 wk.Note : Data incomplete