ฐานข้อมูลอันตรกิริยาระหว่างสมุนไพรกับยาแผนปัจจุบัน

Part Used : ใบ

Activity : DRUG INTERACTION

Solvent/Active Compound : Egb761

Type of experiment : in vivo

Type of animal : rabbit

Type of study : -

N(Total) : -

N(Treatment) : -

Sex : -

Age : -

Route : Intravenous

Dose/Conc.(herb) : Egb761 40 mg/kg + dipyridamole 0.8 mg/kg

Duration : -

Type of interaction : Pharmacodynamics

Interaction with drug : Dipyridamole

Dose/Conc.(drug) : -

Result : Positive

Remark :

Note : - 35 rabbits were divided randomly into 5 groups: Group A (sham group), Group B (model group), Group C (treated with dipyridamole 0.8 mg/kg), Group D (treated with Egb761, 40 mg/kg) and Group E (treated with Egb761 40 mg/kg combined with dipyridamole 0.8 mg/kg). - Results : Both Egb761 and dipyridamole could increase myocardial iNOS expression in transcriptive and translative levels in rabbits after myocardial ischemia-reperfusion injury, and the combined treatment of them shows a more significant effect. - Data incomplete.

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