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UMBELLIFERAE Foeniculum vulgare Mill.

Synonym

UMBELLIFERAE Ligusticum foeniculum (L.) Crantz
UMBELLIFERAE Meum foeniculum (L.) Spreng.
UMBELLIFERAE Selinum foeniculum E.H.L. Krause
UMBELLIFERAE Tenoria romana Schk. ex Spreng.
UMBELLIFERAE Anethum foeniculum L.
UMBELLIFERAE Foeniculum capillaceum Gilib.
UMBELLIFERAE Foeniculum foeniculum (L.) H.Karst.
UMBELLIFERAE Foeniculum officinale All.

Thai / English name

เทียนแกลบ*

[1-3] of 3 article(s) found

หน้า 1

[1] EFFECTS OF MACE AND NUTMEG ON HUMAN CYTOCHROME P450 3A4 AND 2C9 ACTIVITY.
KIMURA Y,ITO H,HATANO T
BIOL PHARM BULL 2010 Vol.33(12),1977-82 $33078 [Full]

Part Used : ไม่ระบุ
Activity : DRUG INTERACTION

Solvent/Active Compound : -

Type of experiment : in vitro
Type of animal : -

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : -
Dose/Conc.(herb) : 100 microgram/ml

Duration : -
Type of interaction : Pharmacokinetics

Interaction with drug : -
Dose/Conc.(drug) : -

Result : Positive

Remark :

[2] IN VITRO INHIBITION OF HUMAN CYP1A2, CYP2D6, AND CYP3A4 BY SIX HERBS COMMONLY USED IN PREGNANCY.
ASTRID JORDET LANGHAMMERAND ODD GEORG NILSEN
PHYTOTHER RES 2014 Vol.28(),603-10 $50122 [Full]

Part Used : -
Activity : DRUG INTERACTION

Solvent/Active Compound : water

Type of experiment : in vitro
Type of animal : -

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : -
Dose/Conc.(herb) : Herbal solution (100 microlitre, seven different concentrations for each herb ranging from 4 to 28000 microgram/ml in 4% ethanol)

Duration : -
Type of interaction : Pharmacokinetics

Interaction with drug : -
Dose/Conc.(drug) : -

Result : Positive

Remark : The IC50 constants of fennel extract for CYP1A2, CYP2D6, and CYP3A4 inhibition were 115+/-11, 23+/-2, and 40+/-4 microgram/ml, respectively.

[3] FENNEL AND RASPBERRY LEAF AS POSSIBLE INHIBITORS OF ACETAMINOPHEN OXIDATION.
ASTRID JORDET LANGHAMMER,ODD GEORG NILSEN
PHYTOTHER RES 2014 Vol.28(),1573-6 $52383 [Full]

Part Used : ผล
Activity : DRUG INTERACTION

Solvent/Active Compound : Aqueous

Type of experiment : in vitro
Type of animal : -

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : -
Dose/Conc.(herb) : 4-4000 microgram/ml

Duration : -
Type of interaction : Pharmacokinetics

Interaction with drug : -
Dose/Conc.(drug) : -

Result : Positive

Remark : Fennel tea fully inhitbited CYP2E1 activity in vitro with IC50 23+-/4 microgram/ml. The data suggest that fennel has a significant potential of inhibiting all the major metabolic pathways for acetaminophen oxidation and N-acetyl-p-benzoquinone imine formation.

หน้า 1

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