Synonym |
Thai / English name |
Part Used : ไม่ระบุActivity : CYP2C INHIBITIONSolvent/Active Compound : QuercetinType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 1-100 micromolarDuration : -Type of interaction : PharmacokineticsInteraction with drug : TolbutamideDose/Conc.(drug) : 1 millimolarResult : PositiveRemark : Quercetin produced 92.1%, 44.9% and 15.1% CYP2C inhibition at 100, 10 and 1 micromolar, respectively.
Part Used : ไม่ระบุActivity : CYP2C INHIBITIONSolvent/Active Compound : KaempferolType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 1-100 micromolarDuration : -Type of interaction : PharmacokineticsInteraction with drug : TolbutamideDose/Conc.(drug) : 1 millimolarResult : PositiveRemark : Kaempferol produced 73.1% and 52.5% CYP2C inhibition at 100 and 10 micromolar, respectively. However, no significant effect was observed in the presence of 1 micromolar of this compound.
Part Used : ไม่ระบุActivity : CYP2C INHIBITIONSolvent/Active Compound : FisetinType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 1-100 micromolarDuration : -Type of interaction : PharmacokineticsInteraction with drug : TolbutamideDose/Conc.(drug) : 1 millimolarResult : PositiveRemark : Fisetin produced 73.0% CYP2C inhibition at 100 micromolar. However, no significant effect was observed in the presence of 10 and 1 micromolar of this compound.
Part Used : ไม่ระบุActivity : CYP2C INHIBITIONSolvent/Active Compound : myricetinType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 1-100 micromolarDuration : -Type of interaction : PharmacokineticsInteraction with drug : TolbutamideDose/Conc.(drug) : 1 millimolarResult : PositiveRemark : Myricetin produced 89.0% CYP2C inhibition at 100 micromolar. However, no significant effect was observed in the presence of 10 and 1 micromolar of this compound.
Part Used : ไม่ระบุActivity : CYP2C INHIBITIONSolvent/Active Compound : IsoquercitrinType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 1-100 micromolarDuration : -Type of interaction : PharmacokineticsInteraction with drug : TolbutamideDose/Conc.(drug) : 1 millimolarResult : PositiveRemark : Isoquercitrin produced 62.0% CYP2C inhibition at 100 micromolar. Howerver, no significant effect was observed in the presence of 10 and 1 micromolar of this compound.
Part Used : ไม่ระบุActivity : CYP2C INHIBITIONSolvent/Active Compound : QuercitrinType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 1-100 micromolarDuration : -Type of interaction : PharmacokineticsInteraction with drug : TolbutamideDose/Conc.(drug) : 1 millimolarResult : NegativeRemark : Quercitrin failed to inhibit CYP2C activity.