Synonym |
Thai / English name |
Part Used : รากActivity : ANTIBACTERIAL ACTIVITYSolvent/Active Compound : ginsenosides*Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : -Duration : 24 h of incubation at 37 degress celsiusType of interaction : PharmacokineticsInteraction with drug : KanamycinDose/Conc.(drug) : -Result : PositiveRemark : Result: The combination of kanamycin with ginsenosides significantly improved antibacterial activity (MIC=12.5-25 micrograms/mL for MRSA1, 25-100 micrograms/mL for MRSA2, and 50-100 micrograms/mL for MRSA3). FIC indexes had shown the combination of ginsenosides and kanamycin had a synergistic or additive effect againt MRSA.Note : *Compound: Ginsenosides contained Rb1, Rb2, Rc, Rd, Re, Rf, Rg1, Rg2, Rg3, Rh2. The combination effect of commercial antibiotics and ginsenosides was determined by a checkboard assay and the effects were evaluated using fractional inhibitory concentration (FIC) indexs. MRSA= methicillin-resistant Staphylococcus aureus strains.
Part Used : รากActivity : ANTIBACTERIAL ACTIVITYSolvent/Active Compound : ginsenosides*Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : -Duration : 24 h of incubation at 37 degress celsiusType of interaction : PharmacokineticsInteraction with drug : CefotaximeDose/Conc.(drug) : -Result : PositiveRemark : Result: The combination of cefotaxime with ginsenosides significantly improved antibacterial activity (MIC=2.5-50 micrograms/mL for MRSA1, 5-50 micrograms/mL for MRSA2, and 5-50 micrograms/mL for MRSA3), FIC indexes had shown the combination of ginsenosides and cefotaxime had an additive effect againt MRSA.Note : *Compound: Ginsenosides contained Rb1, Rb2, Rc, Rd, Re, Rf, Rg1, Rg2, Rg3, Rh2. The combination effect of commercial antibiotics and ginsenosides was determined by a checkboard assay and the effects were evaluated using fractional inhibitory concentration (FIC) indexs. MRSA= methicillin-resistant Staphylococcus aureus strains.