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Part Used : ไม่ระบุ

Activity : PLATELET ACTIVATING FACTOR BINDING INHIBITION

Solvent/Active Compound : ginsenosides

Type of experiment : in vitro

Type of animal : -

Type of study : -

N(Total) : -

N(Treatment) : -

Sex : -

Age : -

Route : -

Dose/Conc.(herb) : The reaction mixture consisted of 100 microliters platelet suspension, 90 microliters [3H] PAF (0.9 nM, 70000 dpm), wtih or without unlabelled PAF (500-fold radioactive form), and 60 microliters sample or control solution.

Duration : 30 min at room temp

Type of interaction : Pharmacodynamics

Interaction with drug : -

Dose/Conc.(drug) : -

Result : Positive

Remark : 20 (S) and delta 20-ginsenosides Rg3, protpanaxadiol-type saponins, were found to be relatively potent platelet activating factor (PAF) antagonists (IC50 =4.9x10(-5) and 9.2x10 (-5) M, respectively.

Note : Type of experiment: rabbit platelets

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