Part Used : เหง้า
Activity : DRUG INTERACTION
Solvent/Active Compound : 25-hydroxyprotopanaxadiol (25-OH-PPD)
Type of experiment : in vivo
Type of animal : mouse
N(Total) : -
N(Treatment) : -
Route : Non-specified
Dose/Conc.(herb) : -
Duration : -
Type of interaction : Pharmacodynamics
Interaction with drug : Gemcitabine
Dose/Conc.(drug) : -
Remark : Results: In nude mice bearing PC3 xenograft tumors, 25-OH-PPD inhibited tumor growth in a dose dependent manner and could be safely combined with chemotherapeutic agents (taxotere and gemcitabine) and radiation therapy to improve the anti-tumor effects.