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Part Used : ใบActivity : ANTIBACTERIAL ACTIVITYSolvent/Active Compound : Essential oilType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 25 microlitreDuration : 20 hoursType of interaction : PharmacodynamicsInteraction with drug : PiperacillinDose/Conc.(drug) : 25 microlitreResult : PositiveRemark : - MIC of one sample alone for piperacillin (microgram/ml) = 1024, for peppermint (%, v/v) = 2 - MIC of one sample of the most effective combination for piperacillin (microgram/ml) = 64, for peppermint bark (%, v/v) = 0.50 - FIC of antibiotic = 0.063 - FIC of oil = 0.25 - FICI = 0.31Note : The miniumum inhibitory concentration (MIC) values of the bacterial strains under study were determined by means or broth microdilution as stated in CLSI M07-A8. FIC = fraction inhibitory concentration. FICI = the combined effects of the antibiotics and essential oils were calculated and expressed in terms of FIC (FICI= 0.5, synergistic; FICI > 0.5-4.0, no interaction; FICI > 4.0 antagonism).
Part Used : ใบActivity : ANTIBACTERIAL ACTIVITYSolvent/Active Compound : Essential oilType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 25 microlitreDuration : 20 hoursType of interaction : PharmacodynamicsInteraction with drug : AmpicillinDose/Conc.(drug) : 25 microlitreResult : NegativeRemark : - MIC of one sample alone for ampicillin (microgram/ml) = 1024, for peppermint (%, v/v) = 2 - MIC of one sample of the most effective combination for ampicillin (microgram/ml) = 512, for peppermint (%, v/v) = 1 - FIC of antibiotic = 0.50 - FIC of oil = 0.5 - FICI = 1Note : The miniumum inhibitory concentration (MIC) values of the bacterial strains under study were determined by means or broth microdilution as stated in CLSI M07-A8. FIC = fraction inhibitory concentration. FICI = the combined effects of the antibiotics and essential oils were calculated and expressed in terms of FIC (FICI= 0.5, synergistic; FICI > 0.5-4.0, no interaction; FICI > 4.0 antagonism).
Part Used : ใบActivity : ANTIBACTERIAL ACTIVITYSolvent/Active Compound : Essential oilType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 25 microlitreDuration : 20 hoursType of interaction : PharmacodynamicsInteraction with drug : Carbenicillin*/CarindacillinDose/Conc.(drug) : 25 microlitreResult : NegativeRemark : - MIC of one sample alone for carbenicillin (microgram/ml) = 6250, for peppermint (%, v/v) = 2 - MIC of one sample of the most effective combination for carbenicillin (microgram/ml) = 3125, for peppermint (%, v/v) = 0.50 - FIC of antibiotic = 0.5 - FIC of oil = 0.25 - FICI = 0.75Note : The miniumum inhibitory concentration (MIC) values of the bacterial strains under study were determined by means or broth microdilution as stated in CLSI M07-A8. FIC = fraction inhibitory concentration. FICI = the combined effects of the antibiotics and essential oils were calculated and expressed in terms of FIC (FICI= 0.5, synergistic; FICI > 0.5-4.0, no interaction; FICI > 4.0 antagonism).
Part Used : ใบActivity : ANTIBACTERIAL ACTIVITYSolvent/Active Compound : Essential oilType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 25 microlitreDuration : 20 hoursType of interaction : PharmacodynamicsInteraction with drug : CefazolinDose/Conc.(drug) : 25 microlitreResult : NegativeRemark : - MIC of one sample alone for cefazolin (microgram/ml) = 8, for peppermint (%, v/v) = 2 - MIC of one sample of the most effective combination for cefazolin (microgram/ml) = 8, for peppermint (%, v/v) = 2 - FIC of antibiotic = 1 - FIC of oil = 1 - FICI = 2Note : The miniumum inhibitory concentration (MIC) values of the bacterial strains under study were determined by means or broth microdilution as stated in CLSI M07-A8. FIC = fraction inhibitory concentration. FICI = the combined effects of the antibiotics and essential oils were calculated and expressed in terms of FIC (FICI= 0.5, synergistic; FICI > 0.5-4.0, no interaction; FICI > 4.0 antagonism).
Part Used : ใบActivity : ANTIBACTERIAL ACTIVITYSolvent/Active Compound : Essential oilType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 25 microlitreDuration : 20 hoursType of interaction : PharmacodynamicsInteraction with drug : CefuroximeDose/Conc.(drug) : 25 microlitreResult : NegativeRemark : - MIC of one sample alone for cefuroxime (microgram/ml) = 8, for peppermint (%, v/v) = 2 - MIC of one sample of the most effective combination for cefuroxime (microgram/ml) = 0.50, for peppermint (%, v/v) = 1 - FIC of antibiotic = 0.063 - FIC of oil = 0.50 - FICI = 0.56Note : The miniumum inhibitory concentration (MIC) values of the bacterial strains under study were determined by means or broth microdilution as stated in CLSI M07-A8. FIC = fraction inhibitory concentration. FICI = the combined effects of the antibiotics and essential oils were calculated and expressed in terms of FIC (FICI= 0.5, synergistic; FICI > 0.5-4.0, no interaction; FICI > 4.0 antagonism).
Part Used : ใบActivity : ANTIBACTERIAL ACTIVITYSolvent/Active Compound : Essential oilType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 25 microlitreDuration : 20 hoursType of interaction : PharmacodynamicsInteraction with drug : MeropenemDose/Conc.(drug) : 25 microlitreResult : NegativeRemark : - MIC of one sample alone for meropenem (microgram/ml) = 4, for pepermint (%, v/v) = 8 - MIC of one sample of the most effective combination for meropenem (microgram/ml) = 0.50, for cinnamon bark (%, v/v) = 1 - FIC of antibiotic = 0.13 - FIC of oil = 0.13 - FICI = 1.26Note : The miniumum inhibitory concentration (MIC) values of the bacterial strains under study were determined by means or broth microdilution as stated in CLSI M07-A8. FIC = fraction inhibitory concentration. FICI = the combined effects of the antibiotics and essential oils were calculated and expressed in terms of FIC (FICI= 0.5, synergistic; FICI > 0.5-4.0, no interaction; FICI > 4.0 antagonism).
Part Used : ใบActivity : ANTIBACTERIAL ACTIVITYSolvent/Active Compound : Essential oilType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 25 microlitreDuration : 20 hoursType of interaction : PharmacodynamicsInteraction with drug : CeftazidimeDose/Conc.(drug) : 25 microlitreResult : NegativeRemark : - MIC of one sample alone for ceflazidime (microgram/ml) = 32, for peppermint (%, v/v) = 1 - MIC of one sample of the most effective combination for ceflazidime (microgram/ml) = 32, for peppermint (%, v/v) = 1 - FIC of antibiotic = 1 - FIC of oil = 1 - FICI = 2Note : The miniumum inhibitory concentration (MIC) values of the bacterial strains under study were determined by means or broth microdilution as stated in CLSI M07-A8. FIC = fraction inhibitory concentration. FICI = the combined effects of the antibiotics and essential oils were calculated and expressed in terms of FIC (FICI= 0.5, synergistic; FICI > 0.5-4.0, no interaction; FICI > 4.0 antagonism).