ฐานข้อมูลอันตรกิริยาระหว่างสมุนไพรกับยาแผนปัจจุบัน

Part Used : วุ้นจากใบ

Activity : CYP3A4 INHIBITION

Solvent/Active Compound : -

Type of experiment : in vitro

Type of animal : -

Type of study : -

N(Total) : -

N(Treatment) : -

Sex : -

Age : -

Route : -

Dose/Conc.(herb) : -

Duration : -

Type of interaction : Pharmacokinetics

Interaction with drug : -

Dose/Conc.(drug) : -

Result : Positive

Remark : AVJ (Aloe vera juice) extracts showed about twice the inhibitory potency towards both CYP enzymes over the other with IC50 values of 8.35 +/- 0.72 and 12.5 +/- 2.1 mg/mL for CYP3A4 and CYP2D6, respectively.

Note : Ketoconazole used for positive control / Quinidine used for positive control

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