Synonym |
Thai / English name |
Part Used : ไม่ระบุActivity : ANTIPLATELET ACTIVITYSolvent/Active Compound : -Type of experiment : humanType of animal : -Type of study : Case reportN(Total) : 1 (M/F = 0/1)N(Treatment) : 1 (M/F = 0/1)Sex : FemaleAge : 35 yrsRoute : Oral administrationDose/Conc.(herb) : 4 tablets of Aloe vera / dayDuration : 2 weeksType of interaction : PharmacodynamicsInteraction with drug : SevofluraneDose/Conc.(drug) : 0.5-1.3%Result : PositiveRemark : Compounds contained within Aloe vera can cause a reduction in prostaglandin synthesis, which may inhibit secondary aggregation of platelets. Sevoflurane inhibits thromboxane A2 formation by suppression of cyclooxygenase activity, impairs platelet aggregation, and prolongs bleeding. Although the vascularity and size of the hemangioma were the most important factors for the massive intraoperative blood loss, concomitant use of sevoflurane and Aloe vera played a contributory role. An objective causality assessment revealed that this adverse event was possible as a result of the sevoflurane and Aloe vera interaction.
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : humanType of animal : -Type of study : Case reportN(Total) : 1 (M/F = 0/1)N(Treatment) : 1 (M/F = 0/1)Sex : FemaleAge : 35 yrsRoute : Oral administrationDose/Conc.(herb) : 4 tablets of Aloe vera / dayDuration : 2 weeksType of interaction : PharmacodynamicsInteraction with drug : SevofluraneDose/Conc.(drug) : 0.5-1.3%Result : PositiveRemark : Compounds contained within Aloe vera can cause a reduction in prostaglandin synthesis, which may inhibit secondary aggregation of platelets. Sevoflurane inhibits thromboxane A2 formation by suppression of cyclooxygenase activity, impairs platelet aggregation, and prolongs bleeding. Although the vascularity and size of the hemangioma were the most important factors for the massive intraoperative blood loss, concomitant use of sevoflurane and Aloe vera played a contributory role. An objective causality assessment revealed that this adverse event was possible as a result of the sevoflurane and Aloe vera interaction.
Part Used : ไม่ระบุActivity : PROSTAGLANDIN SYNTHESIS INHIBITIONSolvent/Active Compound : -Type of experiment : humanType of animal : -Type of study : Case reportN(Total) : 1 (M/F = 0/1)N(Treatment) : 1 (M/F = 0/1)Sex : FemaleAge : 35 yrsRoute : Oral administrationDose/Conc.(herb) : 4 tablets of Aloe vera / dayDuration : 2 weeksType of interaction : PharmacodynamicsInteraction with drug : SevofluraneDose/Conc.(drug) : 0.5-1.3%Result : PositiveRemark : Compounds contained within Aloe vera can cause a reduction in prostaglandin synthesis, which may inhibit secondary aggregation of platelets. Sevoflurane inhibits thromboxane A2 formation by suppression of cyclooxygenase activity, impairs platelet aggregation, and prolongs bleeding. Although the vascularity and size of the hemangioma were the most important factors for the massive intraoperative blood loss, concomitant use of sevoflurane and Aloe vera played a contributory role. An objective causality assessment revealed that this adverse event was possible as a result of the sevoflurane and Aloe vera interaction.
Part Used : ไม่ระบุActivity : PLATELET AGGREGATION INHIBITIONSolvent/Active Compound : -Type of experiment : humanType of animal : -Type of study : Case reportN(Total) : 1 (M/F = 0/1)N(Treatment) : 1 (M/F = 0/1)Sex : FemaleAge : 35 yrsRoute : Oral administrationDose/Conc.(herb) : 4 tablets of Aloe vera / dayDuration : 2 weeksType of interaction : PharmacodynamicsInteraction with drug : SevofluraneDose/Conc.(drug) : 0.5-1.3%Result : PositiveRemark : Compounds contained within Aloe vera can cause a reduction in prostaglandin synthesis, which may inhibit secondary aggregation of platelets. Sevoflurane inhibits thromboxane A2 formation by suppression of cyclooxygenase activity, impairs platelet aggregation, and prolongs bleeding. Although the vascularity and size of the hemangioma were the most important factors for the massive intraoperative blood loss, concomitant use of sevoflurane and Aloe vera played a contributory role. An objective causality assessment revealed that this adverse event was possible as a result of the sevoflurane and Aloe vera interaction.