ฐานข้อมูลอันตรกิริยาระหว่างสมุนไพรกับยาแผนปัจจุบัน

Part Used : ไม่ระบุ

Activity : DIABETES-INHIBITION OF DEVELOPMENT

Solvent/Active Compound : saponins

Type of experiment : human

Type of animal : -

Type of study : Double-blind trial

N(Total) : 69 (M/F = 38/31)

N(Treatment) : 46 (M/F = 25/21)

Sex : Both sex

Age : 54.8 +/-7.2 years (control = 53.7 +/-6.8 years)

Route : Oral administration

Dose/Conc.(herb) : 6 capsules each time and thrice a day after meals

Duration : 12 weeks

Type of interaction : Pharmacodynamics

Interaction with drug : Sulfonylurea

Dose/Conc.(drug) : -

Result : Positive

Remark : Results: The combined therapy of TFGs with sulfonylureas hypoglycemic drug could lower the blood glucose level and ameliorate clinical symptoms in the treatment of T2DM, and the therapy was relatively safe.

Note : Subject total: patients with type 2 diabetes mellitus (T2DM) not well controlled by sulfonylureas alone were randomly assigned to the treated group (46 cases) and the control group (23 cases). Dose: Trigonella foenum-graecum L. total saponins (TFGs) capsules; 0.35 g/pill, each gram of powder equals to 16 g of crude drug.

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