Part Used : น้ำจากผล
Activity : CYP2D6 INHIBITION
Solvent/Active Compound : aqueous
Type of experiment : in vitro
Type of animal : -
N(Total) : -
N(Treatment) : -
Route : -
Dose/Conc.(herb) : -
Duration : -
Type of interaction : Pharmacokinetics
Interaction with drug : -
Dose/Conc.(drug) : -
Remark : The aqueous extract of Morinda citrifolia inhibited CYP2D6 activity with IC50 value >1000 microgram/ml.
Note : Testosterone 6beta-hydroxylase and dextromethorphan O-demethylase were used as maker of CYP3A4 and CYP2D6 activity, respectively.