| Synonym |
| Thai / English name |
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : humanType of animal : -Type of study : non specifiedN(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : -Duration : -Type of interaction : PharmacokineticsInteraction with drug : Levothyroxine*/T4/L-ThyroxineDose/Conc.(drug) :Result : PositiveRemark : In particular, certain foods and drinks affect the absorption of levothyroxine: in particular, dietary fibers, grapes, soybeans, papaya and coffee reduce the absorption of the drug.Note : Data from review
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : humanType of animal : -Type of study : Cross-sectionN(Total) : 250N(Treatment) : 138Sex : Both sexAge : 69+/-10 yrs.Route : Oral administrationDose/Conc.(herb) : Consumption of herbs at least 4 times per weekDuration : -Type of interaction : PharmacokineticsInteraction with drug : WarfarinDose/Conc.(drug) : -Result : PositiveRemark : Consumption of herbs at least 4 times per week was associated with suboptimal anticoagulation control with warfarin. Patients treated with warfarin should not only be aware of the intake of herbal drugs but also of foods with herbal ingredients such as garlic, ginger, and papaya.Note : Patients with atrial fibrillation (AF) who were prescribed warfarin therapy for at least 6 months before the study were recruited from the medical and cardiac clinics.
Part Used : ยางActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 1.0 mlDuration : -Type of interaction : PharmacodynamicsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : Type of experiment: anticoagulant activity of the plant extracts against whole blood Dose / conc.: The reaction mixture consisted of 0-5 ml fresh dog's blood and varying amounts of plant extract.
Part Used : ยางActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 0.25 mlDuration : -Type of interaction : PharmacodynamicsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : Type of experiment: anticoagulant activity of the plant extracts against whole blood Dose / conc.: The reaction mixture consisted of 0-5 ml fresh dog's blood and varying amounts of plant extract. Result: No Clot. C. papaya is a very potent anticoagulant, but at higher concentrations the extract lyses the clot partially.
Part Used : ยางActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 0.5 mlDuration : -Type of interaction : PharmacodynamicsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : Type of experiment: anticoagulant activity of the plant extracts against whole blood Dose / conc.: The reaction mixture consisted of 0-5 ml fresh dog's blood and varying amounts of plant extract. Result: Lysis C. papaya is a very potent anticoagulant, but at higher concentrations the extract lyses the clot partially.
Part Used : ยางActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 1.0 mlDuration : -Type of interaction : PharmacodynamicsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : Type of experiment: anticoagulant activity of the plant extracts against whole blood Dose / conc.: The reaction mixture consisted of 0-5 ml fresh dog's blood and varying amounts of plant extract. Result: Lysis C. papaya is a very potent anticoagulant, but at higher concentrations the extract lyses the clot partially.
Part Used : ยางActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 0-2 mlDuration : -Type of interaction : PharmacodynamicsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : Type of experiment: anticoagulant activity of the plant extracts against citrated plasma Dose / conc.: The reaction mixture consisted of 0-2 ml each of Russel's viper venom, plant extract and plasma. Result: C. papaya showed anticoagulant activity, though some samples formed a slight precipitate with blood plasma.
Part Used : ยางActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 0-2 mlDuration : -Type of interaction : PharmacodynamicsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : Type of experiment: anticoagulant activity of the plant extracts against oxalated plasma Dose / conc.: The reaction mixture consisted of 0-2 ml each of Russel's viper venom, plant extract and plasma. Result: C. papaya showed anticoagulant activity, though some samples formed a slight precipitate with blood plasma.
