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Part Used : -Activity : P-GLYCOPROTEIN INHIBITIONSolvent/Active Compound : Extract of Phyllanthus emblicaType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 300 microgram/ml of extract of Phyllanthus emblica pH 7.4 phosphate buffer solution with 4% DMSODuration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : NegativeRemark :Note : Data incomplete
Part Used : ผลActivity : P-GLYCOPROTEIN INHIBITIONSolvent/Active Compound : 80% ethanolType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 300 micrograms/mLDuration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : Type of experiment: Caco-2 cell monolayers. - An extract of Andrographis paniculata, Phyllanthus emblica, and Solanum trilobatum showed an inhibitory effect on P-glycoprotein mediated effux of Rho-123 in Coco-2 cells.