Part Used : ไม่ระบุ
Activity : CYP3A2 INHIBITION
Solvent/Active Compound : Maslinic acid
Type of experiment : in vitro
Type of animal : -
N(Total) : -
N(Treatment) : -
Route : -
Dose/Conc.(herb) : 1.25-100 micromolar
Duration : -
Type of interaction : Pharmacokinetics
Interaction with drug : -
Dose/Conc.(drug) : -
Remark : Type of experiment: In rat liver microsomes.
- Maslinic acid inhibited CYP3A2 mediated 6beta-hydroxytestosterone formation (IC20 = 8.77 micromolar).
- Inhibited rat liver CYP3A2 49.6%
Note : - Maslinic acid would have a low potential to cause the possible toxicity and drug interations involving CYP enzymes.