Synonym |
Thai / English name |
Part Used : ใบActivity : DRUG INTERACTIONSolvent/Active Compound : extract of guava leaves (GvEx)Type of experiment : in vivoType of animal : mouseType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : GvEx 250 mg/kgDuration : -Type of interaction : PharmacodynamicsInteraction with drug : AcarboseDose/Conc.(drug) : -Result : PositiveRemark : The GvEx had no effect on the blood glucose-lowering effect of the drugs. However, when GvEx was administered to mice loaded with a high concentration cooked starch (without sucrose) together with acarbose or voglibose at a dose that failed to prevent the increase of the postprandial blood glucose level, there was a significant reduction in the rise of the blood glucose level. These results suggest that GvEx is useful for preventing the increase in the blood glucose level in combination with both acarbose and voglibose without having to increase the dose of these drugs.Note : Data incomplete.
Part Used : ใบActivity : DRUG INTERACTIONSolvent/Active Compound : extract of guava leaves (GvEx)Type of experiment : in vivoType of animal : mouseType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : GvEx 250 mg/kgDuration : -Type of interaction : PharmacodynamicsInteraction with drug : VogliboseDose/Conc.(drug) : -Result : PositiveRemark : The GvEx had no effect on the blood glucose-lowering effect of the drugs. However, when GvEx was administered to mice loaded with a high concentration cooked starch (without sucrose) together with acarbose or voglibose at a dose that failed to prevent the increase of the postprandial blood glucose level, there was a significant reduction in the rise of the blood glucose level. These results suggest that GvEx is useful for preventing the increase in the blood glucose level in combination with both acarbose and voglibose without having to increase the dose of these drugs.Note : Data incomplete.
Part Used : ผลActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : -Duration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark :Note : Data incomplete. Data from abstract.
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : -Duration : -Type of interaction : PharmacokineticsInteraction with drug : CimetidineDose/Conc.(drug) : -Result : PositiveRemark : Type of experiment: Caco-2 cell and porcine jejunum tissue Results: Psidium guajava L. (guava) crude exts. significantly decreased cimetidine efflux in both in vitro models resulting in increased absorptive transport of the drug.Note : Data incomplete