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| Thai / English name |
Part Used : ผลActivity : P-GLYCOPROTEIN INHIBITIONSolvent/Active Compound : -Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : -Duration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : Coco-2 cell monolayers.Note : Data incomplete. Data from abstract.
Part Used : ผลActivity : P-GLYCOPROTEIN INHIBITIONSolvent/Active Compound : -Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : -Duration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : Pig intestinal tissues.Note : Data incomplete. Data from abstract.
Part Used : -Activity : P-GLYCOPROTEIN INHIBITIONSolvent/Active Compound : Extract of Psidium guajavaType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 300, 100, 30 microgram/ml of extract of Psidium guajava in pH 7.4 phosphate buffer solution with 4% DMSODuration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : Result: The extract of Psidium guajava had inhibitory effect on the transepithelial transport of Rho-123 in Caco-2 cell.Note : Data incomplete
Part Used : -Activity : P-GLYCOPROTEIN INHIBITIONSolvent/Active Compound : Extract of Psidium guajavaType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 300 microgram/ml of extract of Psidium guajava in pH 7.4 phosphate buffer solution with 4% DMSODuration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : Result: The extract of Psidium guajava could inhibit Rho-123 transport from serosal to mucosal surfaces of everted rat ileum with comparable inhibitory potential.Note : Data incomplete
Part Used : ใบActivity : P-GLYCOPROTEIN INHIBITIONSolvent/Active Compound : 80% ethanolType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 100 micrograms/mLDuration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : Type of experiment: Caco-2 cell monolayers. Results: curcuminoids and an extract of Psidium guajava showed the highest inhibitory effect on P-glycoprotein mediated efflux of Rho-123 in Caco-2 cells.
Part Used : ใบActivity : P-GLYCOPROTEIN INHIBITIONSolvent/Active Compound : 80% ethanolType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 300 micrograms/mLDuration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : Type of experiment: rat ileum Results: curcuminoids and Psidium guajava could inhibit the efflux mechanism of P-glycoprotein in the rat ileum.
