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COMPOSITAE (ASTERACEAE) Acmella oleracea (L.) R.K. Jansen

Synonym

COMPOSITAE (ASTERACEAE) Spilanthes acmella (L.) Murray

Thai / English name

ผักคราดหัวแหวน*

[1-2] of 2 article(s) found

หน้า 1

[1] INHIBITION OF HUMAN CYTOCHROME P4502E1 BY HERBAL EXTRACTS AND THEIR MAJOR ISOLATED CONSTITUENTS.
WANG Y,CORNELIOUS S,MOULICK K,ET AL.
ABSTRACTS, 56TH SOUTHEAST REGIONAL MEETING OF THE AMERICAN CHEMICAL SOCIETY, RESEARCH TRIANGLE PARK, NC, UNITED STATES, NOVEMBER 10-13 2004 Vol.(), 359726 [Abstract]

Part Used : -
Activity : CYP2E1 INHIBITION

Solvent/Active Compound : -

Type of experiment : in vitro
Type of animal : -

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : -
Dose/Conc.(herb) : -

Duration : -
Type of interaction : Pharmacokinetics

Interaction with drug : -
Dose/Conc.(drug) : -

Result : Negative

Remark : Type of experiment: human liver microsomes Results: Spilanthes acmella inhibit cytochrome P 4502E1.

Note : Data incomplete

[2] EFFECTS OF HERBAL PRODUCTS AND THEIR CONSTITUENTS ON HUMAN CYTOCHROME P4502E1 ACTIVITY.
RANER GM,CORNELIOUS S,MOULICK K,ET AL.
FOOD CHEM TOXICOL 2007 Vol.45(12),2359-65 413570 [Abstract]

Part Used : ไม่ระบุ
Activity : CYP2E1 INHIBITION

Solvent/Active Compound : ethanol/alkylamides

Type of experiment : in vitro
Type of animal : -

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : -
Dose/Conc.(herb) : 25 micromolar

Duration : -
Type of interaction : Pharmacokinetics

Interaction with drug : -
Dose/Conc.(drug) : -

Result : Positive

Remark : The alkylamides present in S. acmella also showed significant inhibition at concns. as low as 25 micromolar.

Note : Data incomplete

หน้า 1

EN

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