ฐานข้อมูลอันตรกิริยาระหว่างสมุนไพรกับยาแผนปัจจุบัน

Part Used : ไม่ระบุ

Activity : CYP2D6 INHIBITION

Solvent/Active Compound : ethanol

Type of experiment : in vitro

Type of animal : -

Type of study : -

N(Total) : -

N(Treatment) : -

Sex : -

Age : -

Route : -

Dose/Conc.(herb) : -

Duration : -

Type of interaction : Pharmacokinetics

Interaction with drug : -

Dose/Conc.(drug) : -

Result : Positive

Remark : The ethanolic extract of Millingtonia hortensis inhibited CYP2D6 activity with IC50 value 33.3+/-8.1 microgram/ml.

Note : Testosterone 6beta-hydroxylase and dextromethorphan O-demethylase were used as maker of CYP3A4 and CYP2D6 activity, respectively.

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