Synonym |
Thai / English name |
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : in vivoType of animal : mouseType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : -Duration : -Type of interaction : PharmacokineticsInteraction with drug : GabapentinDose/Conc.(drug) : -Result : PositiveRemark : A combination of Centalla asiatica (CA) extract with antiepileptic drugs (AEDs) resulted in a reduction in the ED50 of CA extract and concomitant AEDS. The ED50 of intraperitoneally given phyenytoin, valproate and gabapentin, were found to be 13, 14, and 310 mg/kg BW, respectively, when given alone, whereas the corresponding values in the presence of CA extract were 5, 29 and 79 mg/kg BW.Note : Data incomplete
Part Used : ไม่ระบุActivity : ANTICONVULSANT ACTIVITYSolvent/Active Compound : -Type of experiment : in vivoType of animal : mouseType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : -Duration : -Type of interaction : PharmacokineticsInteraction with drug : GabapentinDose/Conc.(drug) : -Result : PositiveRemark : A combination of Centalla asiatica (CA) extract with antiepileptic drugs (AEDs) resulted in a reduction in the ED50 of CA extract and concomitant AEDS. The ED50 of intraperitoneally given phyenytoin, valproate and gabapentin, were found to be 13, 14, and 310 mg/kg BW, respectively, when given alone, whereas the corresponding values in the presence of CA extract were 5, 29 and 79 mg/kg BW.Note : Data incomplete