| Synonym |
| Thai / English name |
Part Used : เมล็ดActivity : IMMUNOMODULATOR ACTIVITYSolvent/Active Compound : -Type of experiment : in vivoType of animal : guinea pigType of study : -N(Total) : 35N(Treatment) : 7Sex : Both sexAge : 2-18 yrsRoute : Oral administrationDose/Conc.(herb) : Nigella sativa 0.08 g daily, orallyDuration : 14 daysType of interaction : PharmacokineticsInteraction with drug : Dexamethasone*/DexamethazoneDose/Conc.(drug) : 5 mg/kg i.p.Result : PositiveRemark : The results showed a preventive effect of Nigella sativa on trecheal responsiveness and lung inflammation of sulfur mustard exposed guinea pigs.Note : Guinea pigs were exposed to diluent solution (control group), inhaled SM (SME group), SME treated with Nigella sativa (SME + N), SME treated with dexamethasone (SME + D) and SME treated with both drugs (SME + N + D), (n = 7 for each group) (1) Control group exposed to diluent's solution (ethanol 5 min, 5M, 2F). (2) Sulfur mustard exposed guinea pigs (100 mg/m3 for 5 min, SME group, 3M, 4F). (3) Sulfur mustard exposed guinea pigs pretreated with Nigella sativa 0.08 g daily, orally (SME + N group, 4M, 3F). (4) Sulfur mustard exposed guinea pigs pretreated with 5 mg/kg i.p. dexamethasone 10 min before exposure to sulfur mustard (SME + D group, 3M, 4F). (5) Sulfur mustard exposed guinea pigs pretreated with both Nigella sativa and dexamethasone (SME + N + D group, 5M, 2F).
Part Used : เมล็ดActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : in vivoType of animal : guinea pigType of study : -N(Total) : 35N(Treatment) : 7Sex : Both sexAge : 2-18 yrsRoute : Oral administrationDose/Conc.(herb) : Nigella sativa 0.08 g daily, orallyDuration : 14 daysType of interaction : PharmacokineticsInteraction with drug : Dexamethasone*/DexamethazoneDose/Conc.(drug) : 5 mg/kg i.p.Result : PositiveRemark : The results showed a preventive effect of Nigella sativa on trecheal responsiveness and lung inflammation of sulfur mustard exposed guinea pigs.Note : Guinea pigs were exposed to diluent solution (control group), inhaled SM (SME group), SME treated with Nigella sativa (SME + N), SME treated with dexamethasone (SME + D) and SME treated with both drugs (SME + N + D), (n = 7 for each group) (1) Control group exposed to diluent's solution (ethanol 5 min, 5M, 2F). (2) Sulfur mustard exposed guinea pigs (100 mg/m3 for 5 min, SME group, 3M, 4F). (3) Sulfur mustard exposed guinea pigs pretreated with Nigella sativa 0.08 g daily, orally (SME + N group, 4M, 3F). (4) Sulfur mustard exposed guinea pigs pretreated with 5 mg/kg i.p. dexamethasone 10 min before exposure to sulfur mustard (SME + D group, 3M, 4F). (5) Sulfur mustard exposed guinea pigs pretreated with both Nigella sativa and dexamethasone (SME + N + D group, 5M, 2F).
Part Used : เมล็ดActivity : INTERLEUKIN-4 FORMATION STIMULATIONSolvent/Active Compound : -Type of experiment : in vivoType of animal : guinea pigType of study : -N(Total) : 35N(Treatment) : 7Sex : Both sexAge : 2-18 yrsRoute : Oral administrationDose/Conc.(herb) : Nigella sativa 0.08 g daily, orallyDuration : 14 daysType of interaction : PharmacokineticsInteraction with drug : Dexamethasone*/DexamethazoneDose/Conc.(drug) : 5 mg/kg i.p.Result : PositiveRemark : The results showed a preventive effect of Nigella sativa on trecheal responsiveness and lung inflammation of sulfur mustard exposed guinea pigs.Note : Guinea pigs were exposed to diluent solution (control group), inhaled SM (SME group), SME treated with Nigella sativa (SME + N), SME treated with dexamethasone (SME + D) and SME treated with both drugs (SME + N + D), (n = 7 for each group) (1) Control group exposed to diluent's solution (ethanol 5 min, 5M, 2F). (2) Sulfur mustard exposed guinea pigs (100 mg/m3 for 5 min, SME group, 3M, 4F). (3) Sulfur mustard exposed guinea pigs pretreated with Nigella sativa 0.08 g daily, orally (SME + N group, 4M, 3F). (4) Sulfur mustard exposed guinea pigs pretreated with 5 mg/kg i.p. dexamethasone 10 min before exposure to sulfur mustard (SME + D group, 3M, 4F). (5) Sulfur mustard exposed guinea pigs pretreated with both Nigella sativa and dexamethasone (SME + N + D group, 5M, 2F).
Part Used : เมล็ดActivity : INTERFERON-GAMMA PRODUCTION STIMULATIONSolvent/Active Compound : -Type of experiment : in vivoType of animal : guinea pigType of study : -N(Total) : 35N(Treatment) : 7Sex : Both sexAge : 2-18 yrsRoute : Oral administrationDose/Conc.(herb) : Nigella sativa 0.08 g daily, orallyDuration : 14 daysType of interaction : PharmacokineticsInteraction with drug : Dexamethasone*/DexamethazoneDose/Conc.(drug) : 5 mg/kg i.p.Result : PositiveRemark : The results showed a preventive effect of Nigella sativa on trecheal responsiveness and lung inflammation of sulfur mustard exposed guinea pigs.Note : Guinea pigs were exposed to diluent solution (control group), inhaled SM (SME group), SME treated with Nigella sativa (SME + N), SME treated with dexamethasone (SME + D) and SME treated with both drugs (SME + N + D), (n = 7 for each group) (1) Control group exposed to diluent's solution (ethanol 5 min, 5M, 2F). (2) Sulfur mustard exposed guinea pigs (100 mg/m3 for 5 min, SME group, 3M, 4F). (3) Sulfur mustard exposed guinea pigs pretreated with Nigella sativa 0.08 g daily, orally (SME + N group, 4M, 3F). (4) Sulfur mustard exposed guinea pigs pretreated with 5 mg/kg i.p. dexamethasone 10 min before exposure to sulfur mustard (SME + D group, 3M, 4F). (5) Sulfur mustard exposed guinea pigs pretreated with both Nigella sativa and dexamethasone (SME + N + D group, 5M, 2F).
