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CRUCIFERAE (BRASSICACEAE) Lepidium sativum L.

Synonym

none ...

Thai / English name

เทียนแดง*

[1-1] of 1 article(s) found

หน้า 1

[1] EFFECTS OF FENUGREEK, GARDEN CRESS, AND BLACK SEED ON THEOPHYLLINE PHARMACOKINETICS IN BEAGLE DOGS.
AL-JENOOBI,FAHAD I.;AHAD,ABDUL;MAHROUS,GAMAL M.;ET AL.
PHARMACEUTICAL BIOLOGY (LONDON, UNITED KINGDOM) 2015 Vol.53(2),296-300 491000 [Abstract]

Part Used : เมล็ด
Activity : EFFECTS ON PHARMACOKINETIC

Solvent/Active Compound : -

Type of experiment : in vivo
Type of animal : dog

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : Oral administration
Dose/Conc.(herb) : 25 g twice daily

Duration : 7 day
Type of interaction : Pharmacokinetics

Interaction with drug : Theophylline*/Aminophylline
Dose/Conc.(drug) : 200 mg

Result : Positive

Remark : Garden cress caused a decrease in Cmax to a lesser extent and delayed Tmax of theophylline (2.01 +/- 0.24 h versus 3.40 +/- 0.74 h), while AUCo-infinity increased by 37.44%

Note : Data incomplete. Beagle dogs received theophylline on first day following with herb for 7 day and on eighth day, theophylline was re-administrated again.

Part Used : เมล็ด
Activity : EFFECTS ON PHARMACOKINETIC

Solvent/Active Compound : -

Type of experiment : in vivo
Type of animal : dog

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : Oral administration
Dose/Conc.(herb) : 7.5 g twice daily

Duration : 7 day
Type of interaction : Pharmacokinetics

Interaction with drug : Theophylline*/Aminophylline
Dose/Conc.(drug) : 200 mg

Result : Positive

Remark : Garden cress caused a decrease in Cmax to a lesser extent and delayed Tmax of theophylline (2.01 +/- 0.24 h versus 3.40 +/- 0.74 h), while AUCo-infinity increased by 37.44%

Note : Data incomplete. Beagle dogs received theophylline on first day following with herb for 7 day and on eighth day, theophylline was re-administrated again.

Part Used : เมล็ด
Activity : EFFECTS ON PHARMACOKINETIC

Solvent/Active Compound : -

Type of experiment : in vivo
Type of animal : dog

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : Oral administration
Dose/Conc.(herb) : 2.5 g twice daily

Duration : 7 day
Type of interaction : Pharmacokinetics

Interaction with drug : Theophylline*/Aminophylline
Dose/Conc.(drug) : 200 mg

Result : Positive

Remark : Garden cress caused a decrease in Cmax to a lesser extent and delayed Tmax of theophylline (2.01 +/- 0.24 h versus 3.40 +/- 0.74 h), while AUCo-infinity increased by 37.44%

Note : Data incomplete. Beagle dogs received theophylline on first day following with herb for 7 day and on eighth day, theophylline was re-administrated again.

หน้า 1

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