Synonym |
Thai / English name |
Part Used : ผลActivity : DRUG INTERACTIONSolvent/Active Compound : Pomegranate methanolic extract (PGME)Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : -Duration : -Type of interaction : PharmacodynamicsInteraction with drug : GentamicinDose/Conc.(drug) : -Result : PositiveRemark : Using this combination, cell viability was reduced by 99.9% and 72.5% in methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-sensitive Staphylococcus aureus (MSSA) populations, respectively. PGME increased the post-antibiotic effect (PAE) of ampicillin from 3 to 7 hours. In addition, PGME demonstrated the potential to either inhibit the efflux pump NorA or to enhance the influx of the drug.Note : Data in complete.