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Part Used : เมล็ด

Activity : CYTOCHROME P450 LEVEL DECREASE

Solvent/Active Compound : total parenteral nutrition (TPN)*

Type of experiment : in vivo

Type of animal : rat

Type of study : -

N(Total) : -

N(Treatment) : -

Sex : -

Age : -

Route : Intravenous

Dose/Conc.(herb) : -

Duration : 4 days

Type of interaction : Pharmacokinetics

Interaction with drug : -

Dose/Conc.(drug) : -

Result : Positive

Remark : Result: The levels of expression of mRNA for cytochrome P450 species in the liver of the rats were kept at approx. 32-84% that in controls not receiving TPN, while those in rats receiving TPN without the lipid emulsion were much lower (approx. 1.3-31%)

Note : *An infusion soln. contg. amino acids and electrolytes was mixed with a lipid emulsion (cont. glucose, soybean oil, egg yolk lecithin, and L-histidine) and vitamins to give a total parenteral nutrition (TPN) soln. Data incomplete

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