ฐานข้อมูลอันตรกิริยาระหว่างสมุนไพรกับยาแผนปัจจุบัน

Part Used : ไม่ระบุ

Activity : CYP1A1 INHIBITION

Solvent/Active Compound : soybean protein isolate (SPI)

Type of experiment : in vivo

Type of animal : rat

Type of study : -

N(Total) : -

N(Treatment) : -

Sex : -

Age : -

Route : Oral administration

Dose/Conc.(herb) : -

Duration : -

Type of interaction : Pharmacokinetics

Interaction with drug : -

Dose/Conc.(drug) : -

Result : Positive

Remark : Decreased 7,12-dimethylbenz[a]anthracene induced hepatic cytochrome-P 450 1A1 (CYP1A1), apoprotein, and mRNA expression were found along with decreased binding of aryl hydrocarbon receptor (AhR)-AhR nuclear translocator complex to CYP1A1 gene promoter in SPI + rats compared with casein- or SPI-rats.

Note : Data incomplete

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