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| Thai / English name |
Part Used : ไม่ระบุActivity : CYP2C INHIBITIONSolvent/Active Compound : GenisteinType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 1-100 micromolarDuration : -Type of interaction : PharmacokineticsInteraction with drug : TolbutamideDose/Conc.(drug) : 1 millimolarResult : PositiveRemark : Genistein produced 82.8%, 67.8% and 49.7% CYP2C inhibition at 100, 10 and 1 micromolar, respectively.
Part Used : ไม่ระบุActivity : CYP2C INHIBITIONSolvent/Active Compound : DaidzeinType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 1-100 micromolarDuration : -Type of interaction : PharmacokineticsInteraction with drug : TolbutamideDose/Conc.(drug) : 1 millimolarResult : PositiveRemark : Daidzein produced 24.6% CYP2C inhibition at 100 micromolar. However, no significant effect was observed in the presence of 10 and 1 micromolar of this compound.
Part Used : ไม่ระบุActivity : CYP2C INHIBITIONSolvent/Active Compound : DaidzinType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 1-100 micromolarDuration : -Type of interaction : PharmacokineticsInteraction with drug : TolbutamideDose/Conc.(drug) : 1 millimolarResult : NegativeRemark : Daidzin failed to inhibit CYP2C activity.
