| Synonym |
| Thai / English name |
Part Used : เมล็ดActivity : CYP1A2 INDUCTIONSolvent/Active Compound : Soy isoflavoneType of experiment : in vivoType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 300 mg of isoflavone/kg of dietDuration : 4 weeksType of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : Soy isoflavone did not affect the mRNA abundance of all CYPS.Note : Soy isoflavones. A fermented soybean extract (FSBE) rich in the two major isoflavone aglycones, genistein and daidzein. This FSBE contained 155 mg/g of genistein, 127 mg/g of daidzein, 18 mg/g of glycitein and less than 1 mg/g of genistin, daidzin and glycytin.
Part Used : เมล็ดActivity : CYP1A2 INDUCTIONSolvent/Active Compound : Soy isoflavoneType of experiment : in vivoType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 100 mg of isoflavone/kg of dietDuration : 4 weeksType of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : The gene expression of CYP2C11 and CYP3A2 from the female rats was at a much lower level than that of the male rats. Dietary isoflavone significantly decreased the gene expression of CYP3A2 and decreased the gene expression of CYP2C11 in the female rats, although there was no significant difference among the groups (P = 0.056775). Dietary isoflavone did not significantly affect the gene expression of the other CYPs in the male and female rats.Note : Soy isoflavones. A fermented soybean extract (FSBE) rich in the two major isoflavone aglycones, genistein and daidzein. This FSBE contained 155 mg/g of genistein, 127 mg/g of daidzein, 18 mg/g of glycitein and less than 1 mg/g of genistin, daidzin and glycytin.
Part Used : เมล็ดActivity : CYP1A2 INDUCTIONSolvent/Active Compound : Soy isoflavoneType of experiment : in vivoType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 200 mg of isoflavone/kg of dietDuration : 4 weeksType of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : The gene expression of CYP2C11 and CYP3A2 from the female rats was at a much lower level than that of the male rats. Dietary isoflavone significantly decreased the gene expression of CYP3A2 and decreased the gene expression of CYP2C11 in the female rats, although there was no significant difference among the groups (P = 0.056775). Dietary isoflavone did not significantly affect the gene expression of the other CYPs in the male and female rats.Note : Soy isoflavones. A fermented soybean extract (FSBE) rich in the two major isoflavone aglycones, genistein and daidzein. This FSBE contained 155 mg/g of genistein, 127 mg/g of daidzein, 18 mg/g of glycitein and less than 1 mg/g of genistin, daidzin and glycytin.
Part Used : เมล็ดActivity : CYP1A2 INDUCTIONSolvent/Active Compound : Soy isoflavoneType of experiment : in vivoType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 300 mg of isoflavone/kg of dietDuration : 4 weeksType of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : The gene expression of CYP2C11 and CYP3A2 from the female rats was at a much lower level than that of the male rats. Dietary isoflavone significantly decreased the gene expression of CYP3A2 and decreased the gene expression of CYP2C11 in the female rats, although there was no significant difference among the groups (P = 0.056775). Dietary isoflavone did not significantly affect the gene expression of the other CYPs in the male and female rats.Note : Soy isoflavones. A fermented soybean extract (FSBE) rich in the two major isoflavone aglycones, genistein and daidzein. This FSBE contained 155 mg/g of genistein, 127 mg/g of daidzein, 18 mg/g of glycitein and less than 1 mg/g of genistin, daidzin and glycytin.
