ฐานข้อมูลอันตรกิริยาระหว่างสมุนไพรกับยาแผนปัจจุบัน

Part Used : ใบ

Activity : CYP3A4 INHIBITION

Solvent/Active Compound : Deoxyelephantopin

Type of experiment : in vitro

Type of animal : -

Type of study : -

N(Total) : -

N(Treatment) : -

Sex : -

Age : -

Route : -

Dose/Conc.(herb) : > 10 micromolar

Duration : -

Type of interaction : Pharmacokinetics

Interaction with drug : -

Dose/Conc.(drug) : -

Result : Positive

Remark : When the concentration increases, the CYP3A4 enzymatic activity status to decrease. The greatest decrease in CYP3A4 enzymatic activity, approximately 45.0% relative to the positive control, was observed when cell were treated with deoxyelephantopin at 10 micromolar.

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