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Part Used : ผลActivity : CYP2C19 INHIBITIONSolvent/Active Compound : PiperlonguminineType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 0-100 micromolarDuration : -Type of interaction : PharmacokineticsInteraction with drug : OmeprazoleDose/Conc.(drug) : 20 micromolarResult : PositiveRemark : Piperlonguminine weakly inhibited CYP2C19-catalyzed omeprazole 5-hydroxylation with lC50 values of 63.0 micromolarin pooled human liver microsome.