ฐานข้อมูลอันตรกิริยาระหว่างสมุนไพรกับยาแผนปัจจุบัน

Part Used : ใบ

Activity : CYP1B1 INHIBITION

Solvent/Active Compound : Black tea polyphenol

Type of experiment : in vivo

Type of animal : other

Type of study : -

N(Total) : -

N(Treatment) : -

Sex : -

Age : -

Route : Oral administration

Dose/Conc.(herb) : -

Duration : 4 weeks before carcinogen administration

Type of interaction : Pharmacokinetics

Interaction with drug : -

Dose/Conc.(drug) : -

Result : Positive

Remark : Administration of polyphenon-B significantly decreased tumor incident, oxidative DNA damage, phase I enzymes (CYP450; CYP1A1, 1A2 and 2B isoforms and cytochrome b5) as well as expression of CYP1A1 and CYP1B1 isoforms.

Note : Data incomplete. Type of animal = hamster

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