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Part Used : ใบActivity : CYP3A INHIBITIONSolvent/Active Compound :Type of experiment : in vivoType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : Herbal tea solution (2%, w/v) were prepared stimulating the usual way of brewing tea. Boiled tap water was added to the required weight of tea powder with intermittent stirring for 10 min. The tea brew was than strained through filters to obtain a clear solution, poured in to clean drinking bottles, which were wrapped with light resistant polyethylene sheets, and were given to three groups of rats.Duration : 4 weeksType of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : NegativeRemark :
Part Used : -Activity : CYP3A INHIBITIONSolvent/Active Compound : -Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : -Duration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : Type of experiment: human liver microsomes Results: Tea beverages tested significantly inhibited the midazolam 1'-hydroxylation activity of CYP 3A in a concn.-dependent manner.Note : Data incomplete