ฐานข้อมูลอันตรกิริยาระหว่างสมุนไพรกับยาแผนปัจจุบัน

THEACEAE Camellia sinensis (L.) Kuntze

Synonym

THEACEAE Thea sinensis L.
THEACEAE Camellia sinensis (L.) Kuntze var. assamica (Mast.) Kitam.

Thai / English name

ชา*

[1-1] of 1 article(s) found

หน้า 1

[1] EFFECTS OF CHINESE, JAPANESE AND WESTERN TEA ON HEPATIC P450 ENZYME ACTIVITIES IN RATS.
NIWATTISAIWONG N,LUO X-X,COVILLE PF,ET AL.
DRUG METABOL DRUG INTERACT 2004 Vol.20(1-2),43-56 275073 [Abstract]

Part Used : ใบ
Activity : CYP3A INDUCTION

Solvent/Active Compound : Oolong tea

Type of experiment : in vivo
Type of animal : rat

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : Oral administration
Dose/Conc.(herb) : -

Duration : 4 weeks
Type of interaction : Pharmacokinetics

Interaction with drug : -
Dose/Conc.(drug) : -

Result : Positive

Remark : There were also significant increases (p <0.05) in the activity of CYP3A in livers of animals given Oolong tea (653+/-174 vs 382+/-114 pmol/mg/min).

Note : - Female Wistar rats were divided into five group (n=4 each); each had free access to tea solutions while the control group was supplied with water. Data complete

Part Used : ใบ
Activity : CYP3A INDUCTION

Solvent/Active Compound : Earl Gray tea

Type of experiment : in vivo
Type of animal : rat

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : Oral administration
Dose/Conc.(herb) : -

Duration : 4 weeks
Type of interaction : Pharmacokinetics

Interaction with drug : -
Dose/Conc.(drug) : -

Result : Positive

Remark : There were also significant increases (p <0.05) in the activity of CYP3A in livers of animals given Earl Gray tea (751+/-202 pmol/mg/min).

Note : - Female Wistar rats were divided into five group (n=4 each); each had free access to tea solutions while the control group was supplied with water. Data complete

Part Used : ใบ
Activity : CYP3A INDUCTION

Solvent/Active Compound : Japanese green tea

Type of experiment : in vivo
Type of animal : rat

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : Oral administration
Dose/Conc.(herb) : -

Duration : 4 weeks
Type of interaction : Pharmacokinetics

Interaction with drug : -
Dose/Conc.(drug) : -

Result : Negative

Remark : Japanese green tea had no significant effect on CYP3A activity.

Note : - Female Wistar rats were divided into five group (n=4 each); each had free access to tea solutions while the control group was supplied with water. Data complete

หน้า 1

EN

Web Link ที่เกี่ยวข้อง

ที่อยู่