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Part Used : -

Activity : UDP-GLUCURONYL TRANSFERASE STIMULATION

Solvent/Active Compound : green tea polyphenols (GTP)

Type of experiment : in vivo

Type of animal : rat

Type of study : -

N(Total) : -

N(Treatment) : -

Sex : -

Age : -

Route : Oral administration

Dose/Conc.(herb) : 200 mg/kg

Duration : -

Type of interaction : Pharmacokinetics

Interaction with drug : -

Dose/Conc.(drug) : -

Result : Positive

Remark : On supplementation of GTP by both simultaneous and post treatment mode (200 mg/kg) there was a significant increase in the activity of glutathione-S-transferase and UDP-glucuronyl transferase (Phase II enzymes) and a significant decrease in the activity of cytochrome b5, cytochrome P 450, cytochrome b5 reductase (cyt b5 R), cytochrome P 450 reductase (cyt P 450 R), aryl hydrocarbon hydroxylase (AHH), and DT-diaphorase (DTD) (Phase I enzymes).

Note : Data incomplete

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