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Part Used : ไม่ระบุActivity : APOPTOSIS INHIBITIONSolvent/Active Compound : Green tea extractType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 10 microgram/mL, Green tea extractDuration : -Type of interaction : PharmacodynamicsInteraction with drug : Imipenem*/Imipemide/Imipenemum/N-formimidoylthienamycin/TienamycinDose/Conc.(drug) : 5 micromolarResult : PositiveRemark : Type of experiment: rat thymocyte. Green tea ext. inhibited 5 micromolar etoposide-induced DNA fragmentation and activation of caspase-3-like proteases in thymocytes isolated from Wistar rats (7-8 wk old, male).Note : These results indicate that the ingestion of tea reduces the risk of the side effect of etoposide, which have been clin. administered in chemotherapy as an anticancer drug. Data incomplete
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : Green tea extractType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 10 microgram/mL, Green tea extractDuration : -Type of interaction : PharmacodynamicsInteraction with drug : Imipenem*/Imipemide/Imipenemum/N-formimidoylthienamycin/TienamycinDose/Conc.(drug) : 5 micromolarResult : PositiveRemark : Type of experiment: rat thymocyte. Green tea ext. inhibited 5 micromolar etoposide-induced DNA fragmentation and activation of caspase-3-like proteases in thymocytes isolated from Wistar rats (7-8 wk old, male).Note : These results indicate that the ingestion of tea reduces the risk of the side effect of etoposide, which have been clin. administered in chemotherapy as an anticancer drug. Data incomplete
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : hexane fraction of green tea ext.Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 5 microgram/mLDuration : -Type of interaction : PharmacodynamicsInteraction with drug : Imipenem*/Imipemide/Imipenemum/N-formimidoylthienamycin/TienamycinDose/Conc.(drug) : 5 micromolarResult : PositiveRemark : Type of experiment: rat thymocyte. When the green tea ext. was fractionated into four fractions by successive extn. with hexane, chloroform, Et acetate, and n-butanol; the Et acetate and n-butanol fractions (5 microgram/mL) showed a stronger inhibitory effect compared with the other fractions.Note : These results indicate that the ingestion of tea reduces the risk of the side effect of etoposide, which have been clin. administered in chemotherapy as an anticancer drug. Data incomplete
Part Used : ไม่ระบุActivity : APOPTOSIS INHIBITIONSolvent/Active Compound : hexane fraction of green tea ext.Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 5 microgram/mLDuration : -Type of interaction : PharmacodynamicsInteraction with drug : Imipenem*/Imipemide/Imipenemum/N-formimidoylthienamycin/TienamycinDose/Conc.(drug) : 5 micromolarResult : PositiveRemark : Type of experiment: rat thymocyte. When the green tea ext. was fractionated into four fractions by successive extn. with hexane, chloroform, Et acetate, and n-butanol; the Et acetate and n-butanol fractions (5 microgram/mL) showed a stronger inhibitory effect compared with the other fractions.Note : These results indicate that the ingestion of tea reduces the risk of the side effect of etoposide, which have been clin. administered in chemotherapy as an anticancer drug. Data incomplete
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : chloroform fraction of green tea ext.Type of experiment : in vitroType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 5 microgram/mLDuration : -Type of interaction : PharmacodynamicsInteraction with drug : Imipenem*/Imipemide/Imipenemum/N-formimidoylthienamycin/TienamycinDose/Conc.(drug) : 5 micromolarResult : PositiveRemark : Type of experiment: rat thymocyte. When the green tea ext. was fractionated into four fractions by successive extn. with hexane, chloroform, Et acetate, and n-butanol; the Et acetate and n-butanol fractions (5 microgram/mL) showed a stronger inhibitory effect compared with the other fractions.Note : These results indicate that the ingestion of tea reduces the risk of the side effect of etoposide, which have been clin. administered in chemotherapy as an anticancer drug. Data incomplete
Part Used : ไม่ระบุActivity : APOPTOSIS INHIBITIONSolvent/Active Compound : chloroform fraction of green tea ext.Type of experiment : in vitroType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 5 microgram/mLDuration : -Type of interaction : PharmacodynamicsInteraction with drug : Imipenem*/Imipemide/Imipenemum/N-formimidoylthienamycin/TienamycinDose/Conc.(drug) : 5 micromolarResult : PositiveRemark : Type of experiment: rat thymocyte. When the green tea ext. was fractionated into four fractions by successive extn. with hexane, chloroform, Et acetate, and n-butanol; the Et acetate and n-butanol fractions (5 microgram/mL) showed a stronger inhibitory effect compared with the other fractions.Note : These results indicate that the ingestion of tea reduces the risk of the side effect of etoposide, which have been clin. administered in chemotherapy as an anticancer drug. Data incomplete
Part Used : ไม่ระบุActivity : APOPTOSIS INHIBITIONSolvent/Active Compound : Et acetate fraction of green tea ext.Type of experiment : in vivoType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 5 microgram/mLDuration : -Type of interaction : PharmacodynamicsInteraction with drug : Imipenem*/Imipemide/Imipenemum/N-formimidoylthienamycin/TienamycinDose/Conc.(drug) : 5 micromolarResult : PositiveRemark : Type of experiment: rat thymocyte. When the green tea ext. was fractionated into four fractions by successive extn. with hexane, chloroform, Et acetate, and n-butanol; the Et acetate and n-butanol fractions (5 microgram/mL) showed a stronger inhibitory effect compared with the other fractions.Note : These results indicate that the ingestion of tea reduces the risk of the side effect of etoposide, which have been clin. administered in chemotherapy as an anticancer drug. Data incomplete
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : Et acetate fraction of green tea ext.Type of experiment : in vivoType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 5 microgram/mLDuration : -Type of interaction : PharmacodynamicsInteraction with drug : Imipenem*/Imipemide/Imipenemum/N-formimidoylthienamycin/TienamycinDose/Conc.(drug) : 5 micromolarResult : PositiveRemark : Type of experiment: rat thymocyte. When the green tea ext. was fractionated into four fractions by successive extn. with hexane, chloroform, Et acetate, and n-butanol; the Et acetate and n-butanol fractions (5 microgram/mL) showed a stronger inhibitory effect compared with the other fractions.Note : These results indicate that the ingestion of tea reduces the risk of the side effect of etoposide, which have been clin. administered in chemotherapy as an anticancer drug. Data incomplete
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : n-butanol fraction of green tea ext.Type of experiment : in vitroType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 5 microgram/mL, Green tea extractDuration : -Type of interaction : PharmacodynamicsInteraction with drug : Imipenem*/Imipemide/Imipenemum/N-formimidoylthienamycin/TienamycinDose/Conc.(drug) : 5 micromolarResult : PositiveRemark : Type of experiment: rat thymocyte. When the green tea ext. was fractionated into four fractions by successive extn. with hexane, chloroform, Et acetate, and n-butanol; the Et acetate and n-butanol fractions (5 microgram/mL) showed a stronger inhibitory effect compared with the other fractions.Note : These results indicate that the ingestion of tea reduces the risk of the side effect of etoposide, which have been clin. administered in chemotherapy as an anticancer drug. Data incomplete
Part Used : ไม่ระบุActivity : APOPTOSIS INHIBITIONSolvent/Active Compound : n-butanol fraction of green tea ext.Type of experiment : in vitroType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 5 microgram/mL, Green tea extractDuration : -Type of interaction : PharmacodynamicsInteraction with drug : Imipenem*/Imipemide/Imipenemum/N-formimidoylthienamycin/TienamycinDose/Conc.(drug) : 5 micromolarResult : PositiveRemark : Type of experiment: rat thymocyte. When the green tea ext. was fractionated into four fractions by successive extn. with hexane, chloroform, Et acetate, and n-butanol; the Et acetate and n-butanol fractions (5 microgram/mL) showed a stronger inhibitory effect compared with the other fractions.Note : These results indicate that the ingestion of tea reduces the risk of the side effect of etoposide, which have been clin. administered in chemotherapy as an anticancer drug. Data incomplete