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Part Used : ไม่ระบุActivity : EFFECTS ON PHARMACOKINETICSolvent/Active Compound : -Type of experiment : humanType of animal : -Type of study : Open trialN(Total) :N(Treatment) :Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : 0.3 g ext./250 mLDuration : -Type of interaction : PharmacokineticsInteraction with drug : Folic acid*/Folate/Pteroylglutamic acid/Vitamin M/FolacidDose/Conc.(drug) : 0.4 mgResult : PositiveRemark : At the 0.4 mg folic acid dose, green and black tea reduced the mean Cmax of serum folate by 39.2% and 38.6%, and the mean AUCo-infinity by 26.6% and 17.9%, resp.Note : Data incomplete Subjects: healthy volunteers - The present results suggest an in vivo interaction between tea and folic acid with even low concns. of green and black tea exts. yielding decreased bioavailabilites of folic acid.
Part Used : ไม่ระบุActivity : EFFECTS ON PHARMACOKINETICSolvent/Active Compound : -Type of experiment : humanType of animal : -Type of study : Cross overN(Total) :N(Treatment) :Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : 0.3 g ext./250 mLDuration : -Type of interaction : PharmacokineticsInteraction with drug : Folic acid*/Folate/Pteroylglutamic acid/Vitamin M/FolacidDose/Conc.(drug) : 0.4 mgResult : PositiveRemark : At the 0.4 mg folic acid dose, green and black tea reduced the mean Cmax of serum folate by 39.2% and 38.6%, and the mean AUCo-infinity by 26.6% and 17.9%, resp.Note : Data incomplete Subjects: healthy volunteers - The present results suggest an in vivo interaction between tea and folic acid with even low concns. of green and black tea exts. yielding decreased bioavailabilites of folic acid.
Part Used : ไม่ระบุActivity : EFFECTS ON PHARMACOKINETICSolvent/Active Compound : -Type of experiment : humanType of animal : -Type of study : Open trialN(Total) :N(Treatment) :Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : 0.3 g ext./250 mLDuration : -Type of interaction : PharmacokineticsInteraction with drug : Folic acid*/Folate/Pteroylglutamic acid/Vitamin M/FolacidDose/Conc.(drug) : 5 mgResult : PositiveRemark : At the 5 mg folic acid dose, the mean Cmax of serum folate was reduced by 27.4% and the mean AUCo-infinity was decreased significantly by 39.9% by the co-application of green tea.Note : Data incomplete Subjects: healthy volunteers - The present results suggest an in vivo interaction between tea and folic acid with even low concns. of green and black tea exts. yielding decreased bioavailabilites of folic acid.
Part Used : ไม่ระบุActivity : EFFECTS ON PHARMACOKINETICSolvent/Active Compound : -Type of experiment : humanType of animal : -Type of study : Cross overN(Total) :N(Treatment) :Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : 0.3 g ext./250 mLDuration : -Type of interaction : PharmacokineticsInteraction with drug : Folic acid*/Folate/Pteroylglutamic acid/Vitamin M/FolacidDose/Conc.(drug) : 5 mgResult : PositiveRemark : At the 5 mg folic acid dose, the mean Cmax of serum folate was reduced by 27.4% and the mean AUCo-infinity was decreased significantly by 39.9% by the co-application of green tea.Note : Data incomplete Subjects: healthy volunteers - The present results suggest an in vivo interaction between tea and folic acid with even low concns. of green and black tea exts. yielding decreased bioavailabilites of folic acid.
