Synonym |
Thai / English name |
Part Used : -Activity : PSA(PROSTATE-SPECIFIC ANTIGEN) PRODUCTION INHIBITIONSolvent/Active Compound : green tea polyphenolsType of experiment : in vivoType of animal : mouseType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : 0.1% in drinking waterDuration : -Type of interaction : P.Kinetics & P.DynamicsInteraction with drug : CelecoxibDose/Conc.(drug) : 5 mg/kg, i.p., daily, 5 days per weeksResult : PositiveRemark : Type of animal: nude mice Results: Combination treatment with green tea polyphenols and celecoxib resulted in enhanced (a) tumor growth inhibition, (b) lowering of prostate-specific antigen levels, (c) lowering of insulin-like growth factor-l levels, and (d) circulating levels of serum insulin-like growth factor binding protein-3 compared with results of single-agent treatment.Note : Data incomplete
Part Used : -Activity : INSULIN-LIKE GROWTH FACTOR 1 INHIBITIONSolvent/Active Compound : green tea polyphenolsType of experiment : in vivoType of animal : mouseType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : 0.1% in drinking waterDuration : -Type of interaction : P.Kinetics & P.DynamicsInteraction with drug : CelecoxibDose/Conc.(drug) : 5 mg/kg, i.p., daily, 5 days per weeksResult : PositiveRemark : Type of animal: nude mice Results: Combination treatment with green tea polyphenols and celecoxib resulted in enhanced (a) tumor growth inhibition, (b) lowering of prostate-specific antigen levels, (c) lowering of insulin-like growth factor-l levels, and (d) circulating levels of serum insulin-like growth factor binding protein-3 compared with results of single-agent treatment.Note : Data incomplete
Part Used : -Activity : DRUG INTERACTIONSolvent/Active Compound : green tea polyphenolsType of experiment : in vivoType of animal : mouseType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : 0.1% in drinking waterDuration : -Type of interaction : P.Kinetics & P.DynamicsInteraction with drug : CelecoxibDose/Conc.(drug) : 5 mg/kg, i.p., daily, 5 days per weeksResult : PositiveRemark : Type of animal: nude mice Results: Combination treatment with green tea polyphenols and celecoxib resulted in enhanced (a) tumor growth inhibition, (b) lowering of prostate-specific antigen levels, (c) lowering of insulin-like growth factor-l levels, and (d) circulating levels of serum insulin-like growth factor binding protein-3 compared with results of single-agent treatment.Note : Data incomplete
Part Used : -Activity : ANTITUMOR ACTIVITYSolvent/Active Compound : green tea polyphenolsType of experiment : in vivoType of animal : mouseType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : 0.1% in drinking waterDuration : -Type of interaction : P.Kinetics & P.DynamicsInteraction with drug : CelecoxibDose/Conc.(drug) : 5 mg/kg, i.p., daily, 5 days per weeksResult : PositiveRemark : Type of animal: nude mice Results: Combination treatment with green tea polyphenols and celecoxib resulted in enhanced (a) tumor growth inhibition, (b) lowering of prostate-specific antigen levels, (c) lowering of insulin-like growth factor-l levels, and (d) circulating levels of serum insulin-like growth factor binding protein-3 compared with results of single-agent treatment.Note : Data incomplete